2,2-dimethyl-4,5-diaryl-3(2H)furanone derivatives as selective cyclo-oxygenase-2 inhibitors

  • Song Seok Shin
  • , Min Soo Noh
  • , Young Joo Byun
  • , Jin Kyu Choi
  • , Ji Young Kim
  • , Kyung Min Lim
  • , Jun Yong Ha
  • , Jin Kwan Kim
  • , Chang Hoon Lee
  • , Shin Chung

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

A series of 2,2-dimethyl-5-{4-(methylsulfonyl)phenyl}-4-phenyl-3(2H)furanones was prepared and evaluated for their ability to inhibit cyclo-oxygenase-2 (COX-2).

Original languageEnglish
Pages (from-to)165-168
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume11
Issue number2
DOIs
StatePublished - 22 Jan 2001

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