A case of autoimmune progesterone dermatitis presenting as erythema multiforme

Nam Hee Sung, Tae Han Kim, Do Hun Kim, Hyoseung Shin, Ai Young Lee, Seung Ho Lee

Research output: Contribution to journalArticlepeer-review

Abstract

Autoimmune progesterone dermatitis is a rare disorder involving hypersensitivity to progesterone. It is most frequently characterized by recurrent erythema multiforme, eczematous or urticarial eruptions during the luteal phase of the menstrual cycle. It resolves or partially improves after menstruation. Sensitivity is demonstrated by a challenge test with medroxyprogesterone acetate. The therapeutic goal for autoimmune progesterone dermatitis is the suppression of ovulation. Currently, the first-line choice of therapy is a combination oral contraceptive. Here, we report a case of autoimmune progesterone dermatitis that manifested as cyclic bullous eiythema multiforme. A reactive intradermal progesterone test confirmed the diagnosis.

Original languageEnglish
Pages (from-to)631-634
Number of pages4
JournalKorean Journal of Dermatology
Volume53
Issue number8
StatePublished - Sep 2015

Keywords

  • Autoimmune progesterone dermatitis
  • Erythema multiforme

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