A cell-compatible red light-emitting multianalyte chemosensor via three birds, one stone strategy

Subhabrata Mabhai, Malay Dolai, Surya Kanta Dey, Anamika Dhara, Sujata Maiti Choudhury, Bhriguram Das, Satyajit Dey, Atanu Jana, Deb Ranjan Banerjee

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The design and synthesis of red light-emitting multianalyte chemosensors have always been a challenging task because of its specific requirement of coordination pocket and selective fluorescence mechanism. Herein, we develop a chemosensor via “three birds, one stone” strategy in which we can detect three metal ions with one ligand. A highly sensitive new azo functionalized rhodamine based luminescent sensor is synthesized for selective fluorogenic recognition of Al3+, Cr3+, and chromogenic recognition of Cu2+ in ethanol: H2O medium in the red light-emitting zone. Among the guest metals, Cu2+ efficiently quenches the emission whereas Al3+ and Cr3+ induce increased luminescent 4.76 fold for Al3+ and 2.47 fold for Cr3+ through chelation-enhanced fluorescence (CHEF) and photo-induced electron transfer (PET) regulated mechanism with the formation of 1:1 complex. The restricted imine isomerization through complex formation inhibits ongoing PET process with the instantaneous onset of CHEF. The mechanism is in good consonance with NMR (1H & 13C), FT-IR, elemental analysis, DFT, TCSPC, and pH-dependent studies. Micromolar range detection of 1.1 μM, 1.3 μM, and 1.5 μM for Cu2+, Al3+, and Cr3+ respectively, easy penetration into HLCs cells and higher imaging resolution increase its potentiality to assess Al3+ and Cr3+ in vitro. Moreover, paper strip application increases its viability as an onsite naked-eye portable solid probe.

Original languageEnglish
Article number112889
JournalJournal of Photochemistry and Photobiology A: Chemistry
Volume404
DOIs
StatePublished - 1 Jan 2021

Keywords

  • Azobenzene
  • Chemosensor
  • Paramagnetic quenching
  • PET – CHEF
  • Rhodamine

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