TY - JOUR
T1 - A cell-compatible red light-emitting multianalyte chemosensor via three birds, one stone strategy
AU - Mabhai, Subhabrata
AU - Dolai, Malay
AU - Dey, Surya Kanta
AU - Dhara, Anamika
AU - Choudhury, Sujata Maiti
AU - Das, Bhriguram
AU - Dey, Satyajit
AU - Jana, Atanu
AU - Banerjee, Deb Ranjan
N1 - Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2021/1/1
Y1 - 2021/1/1
N2 - The design and synthesis of red light-emitting multianalyte chemosensors have always been a challenging task because of its specific requirement of coordination pocket and selective fluorescence mechanism. Herein, we develop a chemosensor via “three birds, one stone” strategy in which we can detect three metal ions with one ligand. A highly sensitive new azo functionalized rhodamine based luminescent sensor is synthesized for selective fluorogenic recognition of Al3+, Cr3+, and chromogenic recognition of Cu2+ in ethanol: H2O medium in the red light-emitting zone. Among the guest metals, Cu2+ efficiently quenches the emission whereas Al3+ and Cr3+ induce increased luminescent 4.76 fold for Al3+ and 2.47 fold for Cr3+ through chelation-enhanced fluorescence (CHEF) and photo-induced electron transfer (PET) regulated mechanism with the formation of 1:1 complex. The restricted imine isomerization through complex formation inhibits ongoing PET process with the instantaneous onset of CHEF. The mechanism is in good consonance with NMR (1H & 13C), FT-IR, elemental analysis, DFT, TCSPC, and pH-dependent studies. Micromolar range detection of 1.1 μM, 1.3 μM, and 1.5 μM for Cu2+, Al3+, and Cr3+ respectively, easy penetration into HLCs cells and higher imaging resolution increase its potentiality to assess Al3+ and Cr3+ in vitro. Moreover, paper strip application increases its viability as an onsite naked-eye portable solid probe.
AB - The design and synthesis of red light-emitting multianalyte chemosensors have always been a challenging task because of its specific requirement of coordination pocket and selective fluorescence mechanism. Herein, we develop a chemosensor via “three birds, one stone” strategy in which we can detect three metal ions with one ligand. A highly sensitive new azo functionalized rhodamine based luminescent sensor is synthesized for selective fluorogenic recognition of Al3+, Cr3+, and chromogenic recognition of Cu2+ in ethanol: H2O medium in the red light-emitting zone. Among the guest metals, Cu2+ efficiently quenches the emission whereas Al3+ and Cr3+ induce increased luminescent 4.76 fold for Al3+ and 2.47 fold for Cr3+ through chelation-enhanced fluorescence (CHEF) and photo-induced electron transfer (PET) regulated mechanism with the formation of 1:1 complex. The restricted imine isomerization through complex formation inhibits ongoing PET process with the instantaneous onset of CHEF. The mechanism is in good consonance with NMR (1H & 13C), FT-IR, elemental analysis, DFT, TCSPC, and pH-dependent studies. Micromolar range detection of 1.1 μM, 1.3 μM, and 1.5 μM for Cu2+, Al3+, and Cr3+ respectively, easy penetration into HLCs cells and higher imaging resolution increase its potentiality to assess Al3+ and Cr3+ in vitro. Moreover, paper strip application increases its viability as an onsite naked-eye portable solid probe.
KW - Azobenzene
KW - Chemosensor
KW - Paramagnetic quenching
KW - PET – CHEF
KW - Rhodamine
UR - http://www.scopus.com/inward/record.url?scp=85092300540&partnerID=8YFLogxK
U2 - 10.1016/j.jphotochem.2020.112889
DO - 10.1016/j.jphotochem.2020.112889
M3 - Article
AN - SCOPUS:85092300540
SN - 1010-6030
VL - 404
JO - Journal of Photochemistry and Photobiology A: Chemistry
JF - Journal of Photochemistry and Photobiology A: Chemistry
M1 - 112889
ER -