A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering

Changho Chun, Jinmyoung Joo, Donghoon Kwon, Chang Sup Kim, Hyung Joon Cha, Myung Sub Chung, Sangmin Jeon

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL-1.

Original languageEnglish
Pages (from-to)11047-11049
Number of pages3
JournalChemical Communications
Volume47
Issue number39
DOIs
StatePublished - 21 Oct 2011

Fingerprint

Dive into the research topics of 'A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering'. Together they form a unique fingerprint.

Cite this