A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering

Changho Chun; Jinmyoung Joo; Donghoon Kwon; Chang Sup Kim; Hyung Joon Cha; Myung Sub Chung; Sangmin Jeon

doi:10.1039/c1cc14024h

A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering

Changho Chun
, Jinmyoung Joo
, Donghoon Kwon
, Chang Sup Kim
, Hyung Joon Cha
, Myung Sub Chung
, Sangmin Jeon

Department of Chemical and Biochemical Engineering

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL^-1.

Original language	English
Pages (from-to)	11047-11049
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	39
DOIs	https://doi.org/10.1039/c1cc14024h
State	Published - 21 Oct 2011

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10.1039/c1cc14024h

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title = "A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering",

abstract = "A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL-1.",

author = "Changho Chun and Jinmyoung Joo and Donghoon Kwon and Kim, \{Chang Sup\} and Cha, \{Hyung Joon\} and Chung, \{Myung Sub\} and Sangmin Jeon",

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AU - Chun, Changho

AU - Joo, Jinmyoung

AU - Kwon, Donghoon

AU - Kim, Chang Sup

AU - Cha, Hyung Joon

AU - Chung, Myung Sub

AU - Jeon, Sangmin

PY - 2011/10/21

Y1 - 2011/10/21

N2 - A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL-1.

AB - A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL-1.

UR - https://www.scopus.com/pages/publications/80053324168

U2 - 10.1039/c1cc14024h

DO - 10.1039/c1cc14024h

M3 - Article

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AN - SCOPUS:80053324168

SN - 1359-7345

VL - 47

SP - 11047

EP - 11049

JO - Chemical Communications

JF - Chemical Communications

IS - 39

ER -

A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering

Abstract

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