A kinetics study on surfactin production from Bacillus subtilis MTCC 2415 for application in green cosmetics

Neela Gayathri Ganesan, Vivek Rangarajan

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19 Scopus citations

Abstract

The present study is an attempt to throw insight into the significance of the type of nitrogen sources and their uptake pattern on the kinetics of surfactin production by Bacillus subtilis MTCC 2415. Batch kinetics studies revealed that surfactin production was strongly influenced by nitrate ions than ammonium ions. A maximum surfactin concentration of 1.75 g L−1 with YP/S = 0.035 was obtained when the medium was challenged with both NH4+ and NO3 as nitrogen sources with equal nitrogen concentrations. Furthermore, the applicability of surfactin as a powerful emulsifier in cosmetics was demonstrated by formulating a stable nanoemulsion system using coconut oil and bio-active essential oils as green ingredients. The surfactin-stabilized cosmetic nanoformulation remained stable for three months. The average droplet size was 175 ± 15 nm with Polydispersity Index (PDI) of 0.17 ± 0.01 and zeta potential of −55 ± 0.5 mV.

Original languageEnglish
Article number102001
JournalBiocatalysis and Agricultural Biotechnology
Volume33
DOIs
StatePublished - May 2021

Keywords

  • Essential oils
  • Nitrogen sources
  • Oil-in-water nanoemulsion
  • Stable cosmetic formulation
  • Surfactin production kinetics

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