Abstract
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was used to observe folic acid and its derivatives such as tetrahydrofolate and 5-methyltetrahydrofolate in a vitamin tablet and in foods. Folic acid in a vitamin tablet was determined using angiotensin I as an internal reference. Tetrahydrofolic acid, 5-methyltetrahydrofolic acid, and an oxygenated folate were observed from a human blood sample using graphite plate. The results show that these mass spectrometric methods are useful for quickly obtaining a profile of folates.
Original language | English |
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Pages (from-to) | 1308-1312 |
Number of pages | 5 |
Journal | Bulletin of the Korean Chemical Society |
Volume | 24 |
Issue number | 9 |
DOIs | |
State | Published - 20 Sep 2003 |
Keywords
- Blood
- Folate
- Graphite plate
- MALDI-TOF MS
- Vitamin