Analysis of lipids in deciduous teeth by Matrix-Assisted Laser Desorption/ Ionization Mass Spectrometry (MALDI MS)

Yujin Lee; Eunji Seo; Tae Min Park; Kwang Hak Bae; Sangwon Cha

doi:10.5478/MSL.2017.8.4.105

Analysis of lipids in deciduous teeth by Matrix-Assisted Laser Desorption/ Ionization Mass Spectrometry (MALDI MS)

Yujin Lee, Eunji Seo, Tae Min Park, Kwang Hak Bae, Sangwon Cha

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Recently, deciduous teeth have been proposed as a promising biomatrix for estimating internal and external chemical exposures of an individual from prenatal periods to early childhood. Therefore, detection of organic chemicals in teeth has received increasing attention. Organic materials in tooth matrix are mostly collagen type proteins, but lipids and other small organic chemicals are also present in the tooth matrix. In this study, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) was employed to obtain lipid fingerprints from deciduous teeth. Phospholipids and triacylglcerols (TAGs) from deciduous teeth were successfully detected by MALDI MS with 2,5-dihydroxybenzoic acid (DHB) or gold nanoparticle (AuNP) as a matrix.

Original language	English
Pages (from-to)	105-108
Number of pages	4
Journal	Mass Spectrometry Letters
Volume	8
Issue number	4
DOIs	https://doi.org/10.5478/MSL.2017.8.4.105
State	Published - Dec 2017

Keywords

Deciduous teeth
Gold nanoparticle
MALDI
Phospholipid
Triacylglycerol

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10.5478/MSL.2017.8.4.105

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title = "Analysis of lipids in deciduous teeth by Matrix-Assisted Laser Desorption/ Ionization Mass Spectrometry (MALDI MS)",

abstract = "Recently, deciduous teeth have been proposed as a promising biomatrix for estimating internal and external chemical exposures of an individual from prenatal periods to early childhood. Therefore, detection of organic chemicals in teeth has received increasing attention. Organic materials in tooth matrix are mostly collagen type proteins, but lipids and other small organic chemicals are also present in the tooth matrix. In this study, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) was employed to obtain lipid fingerprints from deciduous teeth. Phospholipids and triacylglcerols (TAGs) from deciduous teeth were successfully detected by MALDI MS with 2,5-dihydroxybenzoic acid (DHB) or gold nanoparticle (AuNP) as a matrix.",

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AU - Lee, Yujin

AU - Seo, Eunji

AU - Park, Tae Min

AU - Bae, Kwang Hak

AU - Cha, Sangwon

N1 - Publisher Copyright: © Korean Society for Mass Spectrometry.

PY - 2017/12

Y1 - 2017/12

N2 - Recently, deciduous teeth have been proposed as a promising biomatrix for estimating internal and external chemical exposures of an individual from prenatal periods to early childhood. Therefore, detection of organic chemicals in teeth has received increasing attention. Organic materials in tooth matrix are mostly collagen type proteins, but lipids and other small organic chemicals are also present in the tooth matrix. In this study, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) was employed to obtain lipid fingerprints from deciduous teeth. Phospholipids and triacylglcerols (TAGs) from deciduous teeth were successfully detected by MALDI MS with 2,5-dihydroxybenzoic acid (DHB) or gold nanoparticle (AuNP) as a matrix.

AB - Recently, deciduous teeth have been proposed as a promising biomatrix for estimating internal and external chemical exposures of an individual from prenatal periods to early childhood. Therefore, detection of organic chemicals in teeth has received increasing attention. Organic materials in tooth matrix are mostly collagen type proteins, but lipids and other small organic chemicals are also present in the tooth matrix. In this study, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) was employed to obtain lipid fingerprints from deciduous teeth. Phospholipids and triacylglcerols (TAGs) from deciduous teeth were successfully detected by MALDI MS with 2,5-dihydroxybenzoic acid (DHB) or gold nanoparticle (AuNP) as a matrix.

KW - Deciduous teeth

KW - Gold nanoparticle

KW - MALDI

KW - Phospholipid

KW - Triacylglycerol

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DO - 10.5478/MSL.2017.8.4.105

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JO - Mass Spectrometry Letters

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Analysis of lipids in deciduous teeth by Matrix-Assisted Laser Desorption/ Ionization Mass Spectrometry (MALDI MS)

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