Anaplastic large cell lymphoma involving anterior segment of the eye

Choul Y.ong Park; Sang W.on Hwang; Do Y.eun Kim; Hee J.in Huh; Jong Hyun Oh

doi:10.3341/kjo.2014.28.1.108

Anaplastic large cell lymphoma involving anterior segment of the eye

Choul Y.ong Park, Sang W.on Hwang, Do Y.eun Kim, Hee J.in Huh, Jong Hyun Oh

Department of Medicine

Dongguk University

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A 36-year-old woman was diagnosed with anaplastic large cell lymphoma (ALCL) by excisional biopsy of a left frontal skin lesion. During the first cycle of chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone), the patient complained of right ocular pain and inflammation. Cytologic examination using aqueous humor revealed atypical lymphocytes, suggesting intraocular ALCL involvement. Acute angle closure developed in the anterior chamber due to rapid progression of ALCL, causing pupillary block. Laser and surgical interventions were attempted but failed to relieve the pupillary block. Finally, radiation therapy resolved the pupillary block to restore the anterior chamber and normalize intraocular pressure. This is the first case in the English literature of ALCL involving the iris to cause acute secondary angle closure.

Original language	English
Pages (from-to)	108-112
Number of pages	5
Journal	Korean journal of ophthalmology : KJO
Volume	28
Issue number	1
DOIs	https://doi.org/10.3341/kjo.2014.28.1.108
State	Published - 1 Feb 2014

Keywords

Acute angle closure
Anaplastic large cell lymphoma
Eye
Radiotherapy

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10.3341/kjo.2014.28.1.108

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title = "Anaplastic large cell lymphoma involving anterior segment of the eye",

abstract = "A 36-year-old woman was diagnosed with anaplastic large cell lymphoma (ALCL) by excisional biopsy of a left frontal skin lesion. During the first cycle of chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone), the patient complained of right ocular pain and inflammation. Cytologic examination using aqueous humor revealed atypical lymphocytes, suggesting intraocular ALCL involvement. Acute angle closure developed in the anterior chamber due to rapid progression of ALCL, causing pupillary block. Laser and surgical interventions were attempted but failed to relieve the pupillary block. Finally, radiation therapy resolved the pupillary block to restore the anterior chamber and normalize intraocular pressure. This is the first case in the English literature of ALCL involving the iris to cause acute secondary angle closure. ",

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AU - Park, Choul Y.ong

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AU - Oh, Jong Hyun

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AB - A 36-year-old woman was diagnosed with anaplastic large cell lymphoma (ALCL) by excisional biopsy of a left frontal skin lesion. During the first cycle of chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone), the patient complained of right ocular pain and inflammation. Cytologic examination using aqueous humor revealed atypical lymphocytes, suggesting intraocular ALCL involvement. Acute angle closure developed in the anterior chamber due to rapid progression of ALCL, causing pupillary block. Laser and surgical interventions were attempted but failed to relieve the pupillary block. Finally, radiation therapy resolved the pupillary block to restore the anterior chamber and normalize intraocular pressure. This is the first case in the English literature of ALCL involving the iris to cause acute secondary angle closure.

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Anaplastic large cell lymphoma involving anterior segment of the eye

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