Abstract
Amphiphilic graft copolymers consisting of poly(vinyl chloride) (PVC) main chains and poly(4-vinyl pyridine) (P4VP) side chains were synthesized via atom transfer radical polymerization (ATRP) using direct initiation of chlorine atoms. The successful synthesis of PVC-g-P4VP graft copolymers was confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR). Transmission electron microscope (TEM) and small angle X-ray scattering (SAXS) analysis showed that PVC-g-P4VP exhibited microphase-separated, ordered structure with 37.6 nm of domain spacing, which was not observed in neat PVC. For antibacterial applications, the tertiary nitrogen atoms of PVC-g-P4VP was quaternized using 1-bromohexane, as confirmed by FTIR measurements. Bacteria including Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Bacillus cereus (B. cereus), and Pseudomonas aeruginosa (P. aeruginosa) were completely killed in 24 h on the quaternized PVC-g-P4VP (46% grafting) surface, indicating its excellent antibacterial behavior while it showed to be cytotoxic to mammalian cell.
Original language | English |
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Pages (from-to) | 265-274 |
Number of pages | 10 |
Journal | Chinese Journal of Polymer Science (English Edition) |
Volume | 33 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2015 |
Keywords
- Antibacterial property
- Atom transfer radical polymerization
- Graft copolymer
- Membranes
- Quaternized polymer