TY - JOUR
T1 - Antibiotic copper oxide-curcumin nanomaterials for antibacterial applications
AU - Varaprasad, Kokkarachedu
AU - López, Matias
AU - Núñez, Dariela
AU - Jayaramudu, Tippabattini
AU - Sadiku, Emmanuel Rotimi
AU - Karthikeyan, Chandrasekaran
AU - Oyarzúnc, Patricio
N1 - Publisher Copyright:
© 2018 Elsevier B.V.
PY - 2020/2/15
Y1 - 2020/2/15
N2 - In this investigation, novel antibiotic core-shell copper oxide-curcumin nanocomposite materials were designed and developed for biomedical applications. The antibiotic nanocomposite materials were synthesized by using sonication technique. In this process, the bandgap of the nanomaterial was controlled by using CuO and it was confirmed by UV-DRS. The formation of an antibiotic core-shell nanostructures and their surface morphologies were studied with XRD, SEM/TEM. EDS and ATR-FTIR confirmed the existence of copper oxide and biomolecule Cum in the antibiotic nanocomposites. In addition, it was recognised that Cum regulated sufficiently, the CuO antibacterial performance towards selected bacteria, viz: Escherichia coli, Staphylococcus aureus, Shigella dysenteriae and Streptococcus pneumoniae. Moreover, the nanomaterials synthesized did show noble antibacterial activity than the standard amoxicillin antibiotic. The finding of this investigation gives unalloyed support that the antibiotic nanocomposites can be highly promising materials for advanced biomedical applications.
AB - In this investigation, novel antibiotic core-shell copper oxide-curcumin nanocomposite materials were designed and developed for biomedical applications. The antibiotic nanocomposite materials were synthesized by using sonication technique. In this process, the bandgap of the nanomaterial was controlled by using CuO and it was confirmed by UV-DRS. The formation of an antibiotic core-shell nanostructures and their surface morphologies were studied with XRD, SEM/TEM. EDS and ATR-FTIR confirmed the existence of copper oxide and biomolecule Cum in the antibiotic nanocomposites. In addition, it was recognised that Cum regulated sufficiently, the CuO antibacterial performance towards selected bacteria, viz: Escherichia coli, Staphylococcus aureus, Shigella dysenteriae and Streptococcus pneumoniae. Moreover, the nanomaterials synthesized did show noble antibacterial activity than the standard amoxicillin antibiotic. The finding of this investigation gives unalloyed support that the antibiotic nanocomposites can be highly promising materials for advanced biomedical applications.
KW - Antibacterial activity
KW - Antibiotics
KW - CuO nanoparticles
KW - Curcumin
UR - http://www.scopus.com/inward/record.url?scp=85077008866&partnerID=8YFLogxK
U2 - 10.1016/j.molliq.2019.112353
DO - 10.1016/j.molliq.2019.112353
M3 - Article
AN - SCOPUS:85077008866
SN - 0167-7322
VL - 300
JO - Journal of Molecular Liquids
JF - Journal of Molecular Liquids
M1 - 112353
ER -