Aptamers as molecular recognition elements for electrical nanobiosensors

Jeong O. Lee; Hye Mi So; Eun Kyoung Jeon; Hyunju Chang; Keehoon Won; Yong Hwan Kim

doi:10.1007/s00216-007-1643-y

Aptamers as molecular recognition elements for electrical nanobiosensors

Jeong O. Lee, Hye Mi So, Eun Kyoung Jeon, Hyunju Chang, Keehoon Won, Yong Hwan Kim

Department of Chemical and Biochemical Engineering

Research output: Contribution to journal › Article › peer-review

199 Scopus citations

Abstract

Recent advances in nanotechnology have enabled the development of nanoscale sensors that outperform conventional biosensors. This review summarizes the nanoscale biosensors that use aptamers as molecular recognition elements. The advantages of aptamers over antibodies as sensors are highlighted. These advantages are especially apparent with electrical sensors such as electrochemical sensors or those using field-effect transistors. [Figure not available: see fulltext.]

Original language	English
Pages (from-to)	1023-1032
Number of pages	10
Journal	Analytical and Bioanalytical Chemistry
Volume	390
Issue number	4
DOIs	https://doi.org/10.1007/s00216-007-1643-y
State	Published - Feb 2008

Keywords

Aptamers
Electrochemical aptamer sensors
Field-effect transistor aptamer sensors
Nanobiosensors

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Aptamers as molecular recognition elements for electrical nanobiosensors

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