Abstract
NAD analogues can be employed as artificial electron carriers for photoenzymatic synthesis under visible light. Four different NAD analogues that have a 3-substituted pyridine ring have been investigated. 3-Acetylpyridine adenine dinucleotide and 3-pyridinealdehyde adenine dinucleotide were photochemically reduced much more efficiently than NAD, while their reduced products showed coenzyme activity comparable to natural NAD.
Original language | English |
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Pages (from-to) | 5490-5495 |
Number of pages | 6 |
Journal | Chemistry - A European Journal |
Volume | 18 |
Issue number | 18 |
DOIs | |
State | Published - 27 Apr 2012 |
Keywords
- nicotinamide
- photosynthesis
- redox chemistry
- visible light