TY - JOUR
T1 - Author Correction
T2 - GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk (Nature Communications (2017) DOI: 10.1038/s41467-017-01490-8)
AU - Pirastu, Nicola
AU - Joshi, Peter K.
AU - De Vries, Paul S.
AU - Cornelis, Marilyn C.
AU - McKeigue, Paul M.
AU - Keum, Nana
AU - Franceschini, Nora
AU - Colombo, Marco
AU - Giovannucci, Edward L.
AU - Spiliopoulou, Athina
AU - Franke, Lude
AU - North, Kari E.
AU - Kraft, Peter
AU - Morrison, Alanna C.
AU - Esko, Tõnu
AU - Wilson, James F.
N1 - Publisher Copyright:
© 2018 The Author(s).
PY - 2018/12/1
Y1 - 2018/12/1
N2 - We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.
AB - We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.
UR - http://www.scopus.com/inward/record.url?scp=85049342946&partnerID=8YFLogxK
U2 - 10.1038/s41467-018-04857-7
DO - 10.1038/s41467-018-04857-7
M3 - Comment/debate
C2 - 29959320
AN - SCOPUS:85049342946
SN - 2041-1723
VL - 9
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 2536
ER -