Abstract
We present a rapid biogenic method for the production of nanoscale gold particles using pear extract. The formation and stability of pear-derived gold nanoparticles (Pear-AuNPs) were monitored by ultraviolet-visible spectroscopy. Their morphology, elemental composition and crystalline phase were determined by transmission electron microscopy, energydispersive X-ray spectroscopy and selected area electron diffraction. The average core size of crystalline Pear-AuNPs was in the range of 10 ± 5 nm and the observed morphology was spherical. The X-ray photoelectron spectrum showed a strong peak for the pure 'Au' phase. The circular dichroism spectrum indicated the natural capping ability of the pear extract, which generated peptide-gold nanoparticles. These nanoparticles were stable in aqueous solution for two months. A cell viability assay of Pear-AuNPs showed biocompatibility with human embryonic kidney 293 cells. Accordingly, this eco-friendly process for the bio-mimetic production of Pear-AuNPs is nontoxic in nature; consequently, it will find potential application in nano-biotechnology.
| Original language | English |
|---|---|
| Pages (from-to) | 2771-2775 |
| Number of pages | 5 |
| Journal | Bulletin of the Korean Chemical Society |
| Volume | 31 |
| Issue number | 10 |
| DOIs | |
| State | Published - 20 Oct 2010 |
Keywords
- AuNPs
- Biogenic
- Cell viability assay
- Nontoxic green product
