Bone formation of human embryonic stem cells-derived osteogenic cells in PLGA/hydroxyapatite composite scaffold

Soo Hong Lee, Sinae Kim, Sang Soo Kim, Seung Eun Ahn, So Jung Gwak, Byung Soo Kim, Hyung Min Chung

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

1. Osteogenic cells derived from human embryonic stem cells successfully regenerated new bone tissues upon in vivo implantation. 2. The BMP-2-loaded scaffold group showed significantly higher mineralization than the other groups, which demonstrates that BMP-2 played a pivotal role in stimulating mineralization during the bone formation. 3. Thus, hESCs could be used as a good alternative source of cells for bone regeneration, particularly through their introductions into PLGA/HA scaffolds with BMP-2 growth factor for the repair and regeneration of bone tissue.

Original languageEnglish
Title of host publication8th World Biomaterials Congress 2008
Pages1632
Number of pages1
StatePublished - 2008
Event8th World Biomaterials Congress 2008, WBC 2008 - Amsterdam, Netherlands
Duration: 28 May 20081 Jun 2008

Publication series

Name8th World Biomaterials Congress 2008
Volume3

Conference

Conference8th World Biomaterials Congress 2008, WBC 2008
Country/TerritoryNetherlands
CityAmsterdam
Period28/05/081/06/08

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