Carboxymethyl cellulose-based materials for infection control and wound healing: A review

Vimala Kanikireddy, Kokkarachedu Varaprasad, Tippabattini Jayaramudu, Chandrasekaran Karthikeyan, Rotimi Sadiku

Research output: Contribution to journalReview articlepeer-review

308 Scopus citations

Abstract

The development of ideal wound dressing materials with excellent characteristics is currently a major demand in wound therapy. In recent years, carboxymethyl cellulose (CMC)-based wound dressing materials have been of immense attraction due to their noble properties, such as: biocompatibility, biodegradability, tissue resembling, low cost and non-toxic. It is used extensively, in a variety of applications in the biomedical and pharmaceutical fields. The hydrophilic nature of CMC, makes it possible to blend and cross-link with other materials, such as: synthetic polymers, natural polymers and inorganic materials and it enables the preparation of innovative wound dressing biomaterials. Hence, this review, focuses on the intrinsic characteristics of CMC-based wound dressing materials, including hydrogels, films, 3D printing, fibres, gauzes and their recent advancements in chronic wound healing.

Original languageEnglish
Pages (from-to)963-975
Number of pages13
JournalInternational Journal of Biological Macromolecules
Volume164
DOIs
StatePublished - 1 Dec 2020

Keywords

  • Antimicrobial
  • Biomedical
  • Carboxymethyl cellulose
  • Wound dressing

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