Case report: Tolosa-Hunt syndrome—expanding the neuromyelitis optica spectrum disorder phenotype?

Soo Hyun Park, Soo Im Jang, Eun Ja Lee, Nam Hee Kim

Research output: Contribution to journalArticlepeer-review

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathy caused by the autoantibody of aquaporin-4 (AQP4). Herein, we report a case of Tolosa-Hunt syndrome presenting with abducens palsy and AQP4 antibodies. This was a rare case of AQP4-immunoglobulin G seropositivity in a patient with Tolosa-Hunt syndrome. Our findings may expand the clinical phenotype of NMOSD and indicate that clinicians should consider testing for AQP4 antibodies in patients with Tolosa-Hunt syndrome.

Original languageEnglish
Article number1326867
JournalFrontiers in Neurology
Volume15
DOIs
StatePublished - 2024

Keywords

  • AQP4-immunoglobulin G
  • Tolosa-Hunt syndrome
  • abducens palsy
  • aquaporin-4 antibody
  • neuromyelitis optica spectrum disorder
  • optic neuritis

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