Ceramics and bioactive glass as bone graft substitutes

Ki Hyoung Koo, Gun Il Im, Ji Young Kim

Research output: Contribution to journalArticlepeer-review

Abstract

Autograft is the gold standard procedure for grafting with osteoinduction, osteoconduction and osteogenecity. Limitations, however, exist due to donor site morbidity and graft availability. Allograft also has the risk of disease transmission and the poor biological activity. Biomaterials including DBM and BMP showed osteoconductive and/or osteoinductive capacities and are used as a bone graft extender. Synthetic bone graft substitutes, such as ceramic and bioactive glass, share some advantages over autograft and allograft including unlimited supply, easy sterilization and good bioactivity. Thus this article presents an overview of bone graft and bone graft substitutes available for current clinical applications.

Original languageEnglish
Pages (from-to)972-977
Number of pages6
JournalTissue Engineering and Regenerative Medicine
Volume6
Issue number4-11
StatePublished - Jun 2009

Keywords

  • Bioactive glass
  • Bone graft
  • Bone graft substitute
  • Ceramic

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