Abstract
Autograft is the gold standard procedure for grafting with osteoinduction, osteoconduction and osteogenecity. Limitations, however, exist due to donor site morbidity and graft availability. Allograft also has the risk of disease transmission and the poor biological activity. Biomaterials including DBM and BMP showed osteoconductive and/or osteoinductive capacities and are used as a bone graft extender. Synthetic bone graft substitutes, such as ceramic and bioactive glass, share some advantages over autograft and allograft including unlimited supply, easy sterilization and good bioactivity. Thus this article presents an overview of bone graft and bone graft substitutes available for current clinical applications.
Original language | English |
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Pages (from-to) | 972-977 |
Number of pages | 6 |
Journal | Tissue Engineering and Regenerative Medicine |
Volume | 6 |
Issue number | 4-11 |
State | Published - Jun 2009 |
Keywords
- Bioactive glass
- Bone graft
- Bone graft substitute
- Ceramic