Chitosan–silver nanocomposites: New functional biomaterial for health-care applications

Ramasubba Reddy Palem; Nabanita Saha; Ganesh D. Shimoga; Zuzana Kronekova; Monika Sláviková; Petr Saha

doi:10.1080/00914037.2017.1291516

Chitosan–silver nanocomposites: New functional biomaterial for health-care applications

Ramasubba Reddy Palem, Nabanita Saha, Ganesh D. Shimoga, Zuzana Kronekova, Monika Sláviková, Petr Saha

Department of Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Chitosan–silver nanocomposites (CS-HDA-AgNCs) was prepared using chitosan, biogenic silver nanocomposites, and crosslinker, hexamethylene 1,6-di(amino carboxysulfonate) (HDA). The film is flexible and transparent. Its physical, mechanical, thermal, hydrophilicity, and swelling properties were improved by HDA (2.5%). The antimicrobial activity of CS-HDA-AgNCs were not displayed any remarkable zone of inhibition but showed toxic effect in the presence of normal 3T3 fibroblasts and cancer HeLa cells. It decreases to ca. 5–7% for both cell lines. In conclusion, it can be mentioned that the CS-HDA-AgNCs, a kind of new functional biomaterial, could be useful for health-care applications.

Original language	English
Pages (from-to)	1-10
Number of pages	10
Journal	International Journal of Polymeric Materials and Polymeric Biomaterials
Volume	67
Issue number	1
DOIs	https://doi.org/10.1080/00914037.2017.1291516
State	Published - 2 Jan 2018

Keywords

Anticancer activity
chitosan
cytotoxicity
green synthesis
silver nanocomposites

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/00914037.2017.1291516

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title = "Chitosan–silver nanocomposites: New functional biomaterial for health-care applications",

abstract = "Chitosan–silver nanocomposites (CS-HDA-AgNCs) was prepared using chitosan, biogenic silver nanocomposites, and crosslinker, hexamethylene 1,6-di(amino carboxysulfonate) (HDA). The film is flexible and transparent. Its physical, mechanical, thermal, hydrophilicity, and swelling properties were improved by HDA (2.5%). The antimicrobial activity of CS-HDA-AgNCs were not displayed any remarkable zone of inhibition but showed toxic effect in the presence of normal 3T3 fibroblasts and cancer HeLa cells. It decreases to ca. 5–7% for both cell lines. In conclusion, it can be mentioned that the CS-HDA-AgNCs, a kind of new functional biomaterial, could be useful for health-care applications.",

keywords = "Anticancer activity, chitosan, cytotoxicity, green synthesis, silver nanocomposites",

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doi = "10.1080/00914037.2017.1291516",

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T1 - Chitosan–silver nanocomposites

T2 - New functional biomaterial for health-care applications

AU - Palem, Ramasubba Reddy

AU - Saha, Nabanita

AU - Shimoga, Ganesh D.

AU - Kronekova, Zuzana

AU - Sláviková, Monika

AU - Saha, Petr

PY - 2018/1/2

Y1 - 2018/1/2

N2 - Chitosan–silver nanocomposites (CS-HDA-AgNCs) was prepared using chitosan, biogenic silver nanocomposites, and crosslinker, hexamethylene 1,6-di(amino carboxysulfonate) (HDA). The film is flexible and transparent. Its physical, mechanical, thermal, hydrophilicity, and swelling properties were improved by HDA (2.5%). The antimicrobial activity of CS-HDA-AgNCs were not displayed any remarkable zone of inhibition but showed toxic effect in the presence of normal 3T3 fibroblasts and cancer HeLa cells. It decreases to ca. 5–7% for both cell lines. In conclusion, it can be mentioned that the CS-HDA-AgNCs, a kind of new functional biomaterial, could be useful for health-care applications.

AB - Chitosan–silver nanocomposites (CS-HDA-AgNCs) was prepared using chitosan, biogenic silver nanocomposites, and crosslinker, hexamethylene 1,6-di(amino carboxysulfonate) (HDA). The film is flexible and transparent. Its physical, mechanical, thermal, hydrophilicity, and swelling properties were improved by HDA (2.5%). The antimicrobial activity of CS-HDA-AgNCs were not displayed any remarkable zone of inhibition but showed toxic effect in the presence of normal 3T3 fibroblasts and cancer HeLa cells. It decreases to ca. 5–7% for both cell lines. In conclusion, it can be mentioned that the CS-HDA-AgNCs, a kind of new functional biomaterial, could be useful for health-care applications.

KW - Anticancer activity

KW - chitosan

KW - cytotoxicity

KW - green synthesis

KW - silver nanocomposites

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JF - International Journal of Polymeric Materials and Polymeric Biomaterials

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ER -

Chitosan–silver nanocomposites: New functional biomaterial for health-care applications

Abstract

Keywords

UN SDGs

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