Abstract
Bioactivity-guided investigation on whole plant of Euphorbia supina, using LPS-induced Raw264.7 cells, led to the identificaiton of a tannin which was not reported from this plant along with four known constituents (quercetin, astragalin, juglanin and methyl gallate). The structure of the tannin was determined as corilagin by the interpretation of NMR (1D and 2D) and MS spectroscopic data. All the isolates were tested for the inhibitory activity against NO production in LPS-induced Raw264.7 cells. Among the tested isolates, corilagin was found to be the most active compound.
Original language | English |
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Pages (from-to) | 126-129 |
Number of pages | 4 |
Journal | Natural Product Sciences |
Volume | 20 |
Issue number | 2 |
State | Published - 2014 |
Keywords
- Corilagin
- Euphorbia supina
- Euphorbiaceae
- Nitric oxide
- Tannin