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CRISPR-Cas technology for rapid detection of pathogens

  • Hossein Daneshgar
  • , Moein Safarkhani
  • , Soheil Sojdeh
  • , Mojtaba Bagherzadeh
  • , Navid Rabiee
  • Sharif University of Technology
  • Tsinghua University
  • Tsinghua University
  • Saveetha Institute of Medical and Technical Sciences (Deemed to be University)

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations

Abstract

In battling global pathogens like SARS-CoV-2, salmonella, and malaria, rapid and precise detection methods are vital. Traditional approaches often face cost and accessibility challenges, especially in resource-limited areas. Integrating CRISPR-Cas technology into detection processes is a game-changer, offering unparalleled specificity and speed for point-of-care use. This method aligns with Green Biomaterials principles, emphasizing eco-friendliness and resource efficiency. By incorporating green biomaterials, the CRISPR-Cas system becomes more sustainable, efficient, and environmentally sensitive. This integration revolutionizes pathogen detection while promoting environmental stewardship. It not only advances rapid detection but also underscores a commitment to ecological consciousness and sustainability in diagnostics, offering promise for global health.

Original languageEnglish
Article number118174
JournalTrAC - Trends in Analytical Chemistry
Volume185
DOIs
StatePublished - Apr 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 12 - Responsible Consumption and Production
    SDG 12 Responsible Consumption and Production
  3. SDG 13 - Climate Action
    SDG 13 Climate Action

Keywords

  • Biosensors
  • CRISPR-Cas
  • Green biomaterials
  • Pathogens

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