TY - JOUR
T1 - Curcumin nanoformulations for antimicrobial and wound healing purposes
AU - Salehi, Bahare
AU - Rodrigues, Célia F.
AU - Peron, Gregorio
AU - Dall'Acqua, Stefano
AU - Sharifi-Rad, Javad
AU - Azmi, Lubna
AU - Shukla, Ila
AU - Singh Baghel, Uttam
AU - Prakash Mishra, Abhay
AU - Elissawy, Ahmed M.
AU - Singab, Abdel Nasser
AU - Pezzani, Raffaele
AU - Redaelli, Marco
AU - Patra, Jayanta Kumar
AU - Kulandaisamy Venil, Chidambaram
AU - Das, Gitishree
AU - Singh, Deeksha
AU - Kriplani, Priyanka
AU - Venditti, Alessandro
AU - Fokou, Patrick Valere Tsouh
AU - Iriti, Marcello
AU - Amarowicz, Ryszard
AU - Martorell, Miquel
AU - Cruz-Martins, Natália
N1 - Publisher Copyright:
© 2021 John Wiley & Sons, Ltd.
PY - 2021/5
Y1 - 2021/5
N2 - The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half-life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.
AB - The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half-life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.
KW - antimicrobial
KW - curcumin
KW - nanoformulation
KW - nanoparticle
KW - wound healing
UR - http://www.scopus.com/inward/record.url?scp=85101478987&partnerID=8YFLogxK
U2 - 10.1002/ptr.6976
DO - 10.1002/ptr.6976
M3 - Review article
C2 - 33587320
AN - SCOPUS:85101478987
SN - 0951-418X
VL - 35
SP - 2487
EP - 2499
JO - Phytotherapy Research
JF - Phytotherapy Research
IS - 5
ER -