Curcumin nanoformulations for antimicrobial and wound healing purposes

Bahare Salehi; Célia F. Rodrigues; Gregorio Peron; Stefano Dall'Acqua; Javad Sharifi-Rad; Lubna Azmi; Ila Shukla; Uttam Singh Baghel; Abhay Prakash Mishra; Ahmed M. Elissawy; Abdel Nasser Singab; Raffaele Pezzani; Marco Redaelli; Jayanta Kumar Patra; Chidambaram Kulandaisamy Venil; Gitishree Das; Deeksha Singh; Priyanka Kriplani; Alessandro Venditti; Patrick Valere Tsouh Fokou; Marcello Iriti; Ryszard Amarowicz; Miquel Martorell; Natália Cruz-Martins

doi:10.1002/ptr.6976

Curcumin nanoformulations for antimicrobial and wound healing purposes

Bahare Salehi
, Célia F. Rodrigues
, Gregorio Peron
, Stefano Dall'Acqua
, Javad Sharifi-Rad
, Lubna Azmi
, Ila Shukla
, Uttam Singh Baghel
, Abhay Prakash Mishra
, Ahmed M. Elissawy
, Abdel Nasser Singab
, Raffaele Pezzani
, Marco Redaelli
, Jayanta Kumar Patra
, Chidambaram Kulandaisamy Venil
, Gitishree Das
, Deeksha Singh
, Priyanka Kriplani
, Alessandro Venditti
, Patrick Valere Tsouh Fokou

Marcello Iriti, Ryszard Amarowicz, Miquel Martorell, Natália Cruz-Martins

Shahid Beheshti University of Medical Sciences
University of Porto
University of Padua
Universidad del Azuay
CSIR - National Botanical Research Institute
University of Kota
Shobhit University
Ain Shams University
Associazione Italiana per la Ricerca Oncologica di Base
Venetian Institute for Molecular Science and Experimental Technologies
Anna University
Government of Rajasthan
Guru Gobind Singh College of Pharmacy
University of Rome La Sapienza
University of Bamenda
University of Milan
Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences
Universidad de Concepción

Research output: Contribution to journal › Review article › peer-review

58 Scopus citations

Abstract

The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half-life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.

Original language	English
Pages (from-to)	2487-2499
Number of pages	13
Journal	Phytotherapy Research
Volume	35
Issue number	5
DOIs	https://doi.org/10.1002/ptr.6976
State	Published - May 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

antimicrobial
curcumin
nanoformulation
nanoparticle
wound healing

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10.1002/ptr.6976

Cite this

Salehi, B., Rodrigues, C. F., Peron, G., Dall'Acqua, S., Sharifi-Rad, J., Azmi, L., Shukla, I., Singh Baghel, U., Prakash Mishra, A., Elissawy, A. M., Singab, A. N., Pezzani, R., Redaelli, M., Patra, J. K., Kulandaisamy Venil, C., Das, G., Singh, D., Kriplani, P., Venditti, A., ... Cruz-Martins, N. (2021). Curcumin nanoformulations for antimicrobial and wound healing purposes. Phytotherapy Research, 35(5), 2487-2499. https://doi.org/10.1002/ptr.6976

@article{48d9941262d54bc390e8fc7feb35ad56,

title = "Curcumin nanoformulations for antimicrobial and wound healing purposes",

abstract = "The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half-life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.",

keywords = "antimicrobial, curcumin, nanoformulation, nanoparticle, wound healing",

author = "Bahare Salehi and Rodrigues, \{C{\'e}lia F.\} and Gregorio Peron and Stefano Dall'Acqua and Javad Sharifi-Rad and Lubna Azmi and Ila Shukla and \{Singh Baghel\}, Uttam and \{Prakash Mishra\}, Abhay and Elissawy, \{Ahmed M.\} and Singab, \{Abdel Nasser\} and Raffaele Pezzani and Marco Redaelli and Patra, \{Jayanta Kumar\} and \{Kulandaisamy Venil\}, Chidambaram and Gitishree Das and Deeksha Singh and Priyanka Kriplani and Alessandro Venditti and Fokou, \{Patrick Valere Tsouh\} and Marcello Iriti and Ryszard Amarowicz and Miquel Martorell and Nat{\'a}lia Cruz-Martins",

note = "Publisher Copyright: {\textcopyright} 2021 John Wiley \& Sons, Ltd.",

year = "2021",

month = may,

doi = "10.1002/ptr.6976",

language = "English",

volume = "35",

pages = "2487--2499",

journal = "Phytotherapy Research",

issn = "0951-418X",

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Salehi, B, Rodrigues, CF, Peron, G, Dall'Acqua, S, Sharifi-Rad, J, Azmi, L, Shukla, I, Singh Baghel, U, Prakash Mishra, A, Elissawy, AM, Singab, AN, Pezzani, R, Redaelli, M, Patra, JK, Kulandaisamy Venil, C, Das, G, Singh, D, Kriplani, P, Venditti, A, Fokou, PVT, Iriti, M, Amarowicz, R, Martorell, M & Cruz-Martins, N 2021, 'Curcumin nanoformulations for antimicrobial and wound healing purposes', Phytotherapy Research, vol. 35, no. 5, pp. 2487-2499. https://doi.org/10.1002/ptr.6976

TY - JOUR

T1 - Curcumin nanoformulations for antimicrobial and wound healing purposes

AU - Salehi, Bahare

AU - Rodrigues, Célia F.

AU - Peron, Gregorio

AU - Dall'Acqua, Stefano

AU - Sharifi-Rad, Javad

AU - Azmi, Lubna

AU - Shukla, Ila

AU - Singh Baghel, Uttam

AU - Prakash Mishra, Abhay

AU - Elissawy, Ahmed M.

AU - Singab, Abdel Nasser

AU - Pezzani, Raffaele

AU - Redaelli, Marco

AU - Patra, Jayanta Kumar

AU - Kulandaisamy Venil, Chidambaram

AU - Das, Gitishree

AU - Singh, Deeksha

AU - Kriplani, Priyanka

AU - Venditti, Alessandro

AU - Fokou, Patrick Valere Tsouh

AU - Iriti, Marcello

AU - Amarowicz, Ryszard

AU - Martorell, Miquel

AU - Cruz-Martins, Natália

PY - 2021/5

Y1 - 2021/5

N2 - The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half-life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.

AB - The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half-life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.

KW - antimicrobial

KW - curcumin

KW - nanoformulation

KW - nanoparticle

KW - wound healing

UR - https://www.scopus.com/pages/publications/85101478987

U2 - 10.1002/ptr.6976

DO - 10.1002/ptr.6976

M3 - Review article

C2 - 33587320

AN - SCOPUS:85101478987

SN - 0951-418X

VL - 35

SP - 2487

EP - 2499

JO - Phytotherapy Research

JF - Phytotherapy Research

IS - 5

ER -

Curcumin nanoformulations for antimicrobial and wound healing purposes

Abstract

UN SDGs

Keywords

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