Abstract
The multifunctional DNAzyme (Dz) delivery system is developed based on nano-sized graphene oxide (nGO) for simultaneous detection and knockdown of the target gene. The Dz/nGO complex system allowed convenient monitoring of HCV mRNA in living cells and silencing of the HCV gene expression by Dz-mediated catalytic cleavage concurrently.
Original language | English |
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Pages (from-to) | 8241-8243 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 49 |
Issue number | 74 |
DOIs | |
State | Published - 20 Aug 2013 |