Abstract
The intestinal absorption mechanism of amino acid esters of two antiviral drugs was characterized and the potential amino acid esters as an effective strategy targeting a peptide transporter for improving oral drug absorption was studied. The approach provided a new rationale in the prodrug strategy of targeting a peptide transporter via the non-peptidyl amino acid esters and expected to have a great impact on the drug design to improve oral drug absorption.
| Original language | English |
|---|---|
| Pages (from-to) | 259-260 |
| Number of pages | 2 |
| Journal | American Chemical Society, Polymer Preprints, Division of Polymer Chemistry |
| Volume | 40 |
| Issue number | 1 |
| State | Published - Mar 1999 |
| Event | Proceedings of the 1999 ACS Anaheim Meeting - Anaheim, CA, USA Duration: 21 Mar 1999 → 25 Mar 1999 |