TY - JOUR
T1 - Diagnosis of churg-strauss syndrome presented with neuroendocrine carcinoma
T2 - A case report
AU - Park, Dayun
AU - Lee, Ho Jun
AU - Lee, Kwang Hoon
AU - Kwon, Bum Sun
AU - Park, Jin Woo
AU - Nam, Ki Yeun
AU - Lee, Kyoung Hwan
N1 - Publisher Copyright:
© 2017 by Korean Academy of Rehabilitation Medicine.
PY - 2017/6/1
Y1 - 2017/6/1
N2 - Churg-Strauss syndrome (CSS) is a rare systemic vasculitis that affect small and medium-sized blood vessels and is accompanied by asthma, eosinophilia, and peripheral neuropathy. This report describes a case of a 52-year-old man who had a history of sinusitis, asthma, and thymus cancer and who had complained of bilateral lower extremity paresthesia and weakness for a month. Peripheral neuropathy was detected by electrodiagnostic studies. Resection of a mediastinal mass, which was diagnosed as thymic neuroendocrine carcinoma, was performed five months before his visit. After thymectomy, peripheral blood tests revealed a gradual increase in eosinophils. Two months after surgery, he was admitted to the hospital for dyspnea, and nodules of focal consolidation were found in his chest X-ray. One month later, pyoderma occurred in the right shin, and the skin biopsy showed extravascular eosinophilic infiltration. He was diagnosed with CSS after thymectomy, and we report a very rare case of CSS presented with thymic neuroendocrine carcinoma.
AB - Churg-Strauss syndrome (CSS) is a rare systemic vasculitis that affect small and medium-sized blood vessels and is accompanied by asthma, eosinophilia, and peripheral neuropathy. This report describes a case of a 52-year-old man who had a history of sinusitis, asthma, and thymus cancer and who had complained of bilateral lower extremity paresthesia and weakness for a month. Peripheral neuropathy was detected by electrodiagnostic studies. Resection of a mediastinal mass, which was diagnosed as thymic neuroendocrine carcinoma, was performed five months before his visit. After thymectomy, peripheral blood tests revealed a gradual increase in eosinophils. Two months after surgery, he was admitted to the hospital for dyspnea, and nodules of focal consolidation were found in his chest X-ray. One month later, pyoderma occurred in the right shin, and the skin biopsy showed extravascular eosinophilic infiltration. He was diagnosed with CSS after thymectomy, and we report a very rare case of CSS presented with thymic neuroendocrine carcinoma.
KW - Churg-Strauss syndrome
KW - Polyneuropathy
KW - Thymic neuroendocrine carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85021389729&partnerID=8YFLogxK
U2 - 10.5535/arm.2017.41.3.493
DO - 10.5535/arm.2017.41.3.493
M3 - Article
AN - SCOPUS:85021389729
SN - 2234-0645
VL - 41
SP - 493
EP - 497
JO - Annals of Rehabilitation Medicine
JF - Annals of Rehabilitation Medicine
IS - 3
ER -