Diagnosis of churg-strauss syndrome presented with neuroendocrine carcinoma: A case report

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Abstract

Churg-Strauss syndrome (CSS) is a rare systemic vasculitis that affect small and medium-sized blood vessels and is accompanied by asthma, eosinophilia, and peripheral neuropathy. This report describes a case of a 52-year-old man who had a history of sinusitis, asthma, and thymus cancer and who had complained of bilateral lower extremity paresthesia and weakness for a month. Peripheral neuropathy was detected by electrodiagnostic studies. Resection of a mediastinal mass, which was diagnosed as thymic neuroendocrine carcinoma, was performed five months before his visit. After thymectomy, peripheral blood tests revealed a gradual increase in eosinophils. Two months after surgery, he was admitted to the hospital for dyspnea, and nodules of focal consolidation were found in his chest X-ray. One month later, pyoderma occurred in the right shin, and the skin biopsy showed extravascular eosinophilic infiltration. He was diagnosed with CSS after thymectomy, and we report a very rare case of CSS presented with thymic neuroendocrine carcinoma.

Original languageEnglish
Pages (from-to)493-497
Number of pages5
JournalAnnals of Rehabilitation Medicine
Volume41
Issue number3
DOIs
StatePublished - 1 Jun 2017

Keywords

  • Churg-Strauss syndrome
  • Polyneuropathy
  • Thymic neuroendocrine carcinoma

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