Diagnostic performance of the cytomegalovirus (CMV) antigenemia assay in patients with CMV gastrointestinal disease

Eun Young Jang; Seong Yeon Park; Eun Jung Lee; Eun Hee Song; Yong Pill Chong; Sang Oh Lee; Sang Ho Choi; Jun Hee Woo; Yang Soo Kim; Sung Han Kim

doi:10.1086/599116

Diagnostic performance of the cytomegalovirus (CMV) antigenemia assay in patients with CMV gastrointestinal disease

Eun Young Jang, Seong Yeon Park, Eun Jung Lee, Eun Hee Song, Yong Pill Chong, Sang Oh Lee, Sang Ho Choi, Jun Hee Woo, Yang Soo Kim, Sung Han Kim

Department of Medicine

University of Ulsan

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable cases, and 64 (45%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of ≥1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54% (95% confidence interval, 41%-68%) and 88% (95% confidence interval, 77%-94%), respectively.

Original language	English
Pages (from-to)	e121-e124
Journal	Clinical Infectious Diseases
Volume	48
Issue number	12
DOIs	https://doi.org/10.1086/599116
State	Published - 15 Jun 2009

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title = "Diagnostic performance of the cytomegalovirus (CMV) antigenemia assay in patients with CMV gastrointestinal disease",

abstract = "Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable cases, and 64 (45%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of ≥1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54% (95% confidence interval, 41%-68%) and 88% (95% confidence interval, 77%-94%), respectively.",

author = "Jang, {Eun Young} and Park, {Seong Yeon} and Lee, {Eun Jung} and Song, {Eun Hee} and Chong, {Yong Pill} and Lee, {Sang Oh} and Choi, {Sang Ho} and Woo, {Jun Hee} and Kim, {Yang Soo} and Kim, {Sung Han}",

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AU - Park, Seong Yeon

AU - Lee, Eun Jung

AU - Song, Eun Hee

AU - Chong, Yong Pill

AU - Lee, Sang Oh

AU - Choi, Sang Ho

AU - Woo, Jun Hee

AU - Kim, Yang Soo

AU - Kim, Sung Han

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AB - Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable cases, and 64 (45%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of ≥1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54% (95% confidence interval, 41%-68%) and 88% (95% confidence interval, 77%-94%), respectively.

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Diagnostic performance of the cytomegalovirus (CMV) antigenemia assay in patients with CMV gastrointestinal disease

Abstract

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