Diagnostic performance of the cytomegalovirus (CMV) antigenemia assay in patients with CMV gastrointestinal disease

Eun Young Jang; Seong Yeon Park; Eun Jung Lee; Eun Hee Song; Yong Pill Chong; Sang Oh Lee; Sang Ho Choi; Jun Hee Woo; Yang Soo Kim; Sung Han Kim

doi:10.1086/599116

Diagnostic performance of the cytomegalovirus (CMV) antigenemia assay in patients with CMV gastrointestinal disease

Eun Young Jang
, Seong Yeon Park
, Eun Jung Lee
, Eun Hee Song
, Yong Pill Chong
, Sang Oh Lee
, Sang Ho Choi
, Jun Hee Woo
, Yang Soo Kim
, Sung Han Kim

Department of Medicine

University of Ulsan

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable cases, and 64 (45%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of ≥1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54% (95% confidence interval, 41%-68%) and 88% (95% confidence interval, 77%-94%), respectively.

Original language	English
Pages (from-to)	e121-e124
Journal	Clinical Infectious Diseases
Volume	48
Issue number	12
DOIs	https://doi.org/10.1086/599116
State	Published - 15 Jun 2009

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10.1086/599116

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title = "Diagnostic performance of the cytomegalovirus (CMV) antigenemia assay in patients with CMV gastrointestinal disease",

abstract = "Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36\%) confirmed cases, 6 (4\%) probable cases, and 64 (45\%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5\%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of ≥1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54\% (95\% confidence interval, 41\%-68\%) and 88\% (95\% confidence interval, 77\%-94\%), respectively.",

author = "Jang, \{Eun Young\} and Park, \{Seong Yeon\} and Lee, \{Eun Jung\} and Song, \{Eun Hee\} and Chong, \{Yong Pill\} and Lee, \{Sang Oh\} and Choi, \{Sang Ho\} and Woo, \{Jun Hee\} and Kim, \{Yang Soo\} and Kim, \{Sung Han\}",

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doi = "10.1086/599116",

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AU - Jang, Eun Young

AU - Park, Seong Yeon

AU - Lee, Eun Jung

AU - Song, Eun Hee

AU - Chong, Yong Pill

AU - Lee, Sang Oh

AU - Choi, Sang Ho

AU - Woo, Jun Hee

AU - Kim, Yang Soo

AU - Kim, Sung Han

PY - 2009/6/15

Y1 - 2009/6/15

N2 - Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable cases, and 64 (45%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of ≥1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54% (95% confidence interval, 41%-68%) and 88% (95% confidence interval, 77%-94%), respectively.

AB - Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable cases, and 64 (45%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of ≥1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54% (95% confidence interval, 41%-68%) and 88% (95% confidence interval, 77%-94%), respectively.

UR - https://www.scopus.com/pages/publications/66949125047

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SN - 1058-4838

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JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 12

ER -

Diagnostic performance of the cytomegalovirus (CMV) antigenemia assay in patients with CMV gastrointestinal disease

Abstract

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