Diagnostic usefulness of differential time to positivity in neutropenic cancer patients with suspected catheter-related candidemia

Kyeong Min Jo; Sungim Choi; Kyung Hwa Jung; Jung Wan Park; Ji Hyun Yun; Min Jae Kim; Yong Pil Chong; Sang Oh Lee; Sang Ho Choi; Yang Soo Kim; Jun Hee Woo; Jung Hee Lee; Je Hwan Lee; Kyoo Hyung Lee; Sung Han Kim

doi:10.1093/mmy/myz028

Diagnostic usefulness of differential time to positivity in neutropenic cancer patients with suspected catheter-related candidemia

Kyeong Min Jo
, Sungim Choi
, Kyung Hwa Jung
, Jung Wan Park
, Ji Hyun Yun
, Min Jae Kim
, Yong Pil Chong
, Sang Oh Lee
, Sang Ho Choi
, Yang Soo Kim
, Jun Hee Woo
, Jung Hee Lee
, Je Hwan Lee
, Kyoo Hyung Lee
, Sung Han Kim

Department of Medicine

University of Ulsan
Inje University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Methods for distinguishing catheter-related candidemia (CRC) from non-CRC before catheter removal remain limited. We thus evaluated the diagnostic performance of differential time to positivity (DTP) to diagnose CRC in neutropenic cancer patients with suspected CRC. Of the 35 patients enrolled, 15 (43%) with CRC (six definite and nine probable) and 17 (49%) with non-CRC were finally analyzed. Based on the receiver operating characteristic curve, the optimal cutoff value of DTP for diagnosing CRC was ≥1.45 hours with the sensitivity 80% (95% confidence interval [CI], 51-95) and specificity 100% (95% CI, 80-100), respectively.

Original language	English
Pages (from-to)	137-140
Number of pages	4
Journal	Medical Mycology
Volume	58
Issue number	1
DOIs	https://doi.org/10.1093/mmy/myz028
State	Published - 1 Jan 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

candidemia
catheter
diagnosis
differential time to positivity
neutropenia

Access to Document

10.1093/mmy/myz028

Cite this

Jo, K. M., Choi, S., Jung, K. H., Park, J. W., Yun, J. H., Kim, M. J., Chong, Y. P., Lee, S. O., Choi, S. H., Kim, Y. S., Woo, J. H., Lee, J. H., Lee, J. H., Lee, K. H., & Kim, S. H. (2020). Diagnostic usefulness of differential time to positivity in neutropenic cancer patients with suspected catheter-related candidemia. Medical Mycology, 58(1), 137-140. https://doi.org/10.1093/mmy/myz028

@article{7cdcf95688dc4108af5cd2151c558a3e,

title = "Diagnostic usefulness of differential time to positivity in neutropenic cancer patients with suspected catheter-related candidemia",

abstract = "Methods for distinguishing catheter-related candidemia (CRC) from non-CRC before catheter removal remain limited. We thus evaluated the diagnostic performance of differential time to positivity (DTP) to diagnose CRC in neutropenic cancer patients with suspected CRC. Of the 35 patients enrolled, 15 (43\%) with CRC (six definite and nine probable) and 17 (49\%) with non-CRC were finally analyzed. Based on the receiver operating characteristic curve, the optimal cutoff value of DTP for diagnosing CRC was ≥1.45 hours with the sensitivity 80\% (95\% confidence interval [CI], 51-95) and specificity 100\% (95\% CI, 80-100), respectively.",

keywords = "candidemia, catheter, diagnosis, differential time to positivity, neutropenia",

author = "Jo, \{Kyeong Min\} and Sungim Choi and Jung, \{Kyung Hwa\} and Park, \{Jung Wan\} and Yun, \{Ji Hyun\} and Kim, \{Min Jae\} and Chong, \{Yong Pil\} and Lee, \{Sang Oh\} and Choi, \{Sang Ho\} and Kim, \{Yang Soo\} and Woo, \{Jun Hee\} and Lee, \{Jung Hee\} and Lee, \{Je Hwan\} and Lee, \{Kyoo Hyung\} and Kim, \{Sung Han\}",

note = "Publisher Copyright: {\textcopyright} 2020 The Author(s). Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.",

year = "2020",

month = jan,

day = "1",

doi = "10.1093/mmy/myz028",

language = "English",

volume = "58",

pages = "137--140",

journal = "Medical Mycology",

issn = "1369-3786",

publisher = "Oxford University Press",

number = "1",

}

TY - JOUR

T1 - Diagnostic usefulness of differential time to positivity in neutropenic cancer patients with suspected catheter-related candidemia

AU - Jo, Kyeong Min

AU - Choi, Sungim

AU - Jung, Kyung Hwa

AU - Park, Jung Wan

AU - Yun, Ji Hyun

AU - Kim, Min Jae

AU - Chong, Yong Pil

AU - Lee, Sang Oh

AU - Choi, Sang Ho

AU - Kim, Yang Soo

AU - Woo, Jun Hee

AU - Lee, Jung Hee

AU - Lee, Je Hwan

AU - Lee, Kyoo Hyung

AU - Kim, Sung Han

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Methods for distinguishing catheter-related candidemia (CRC) from non-CRC before catheter removal remain limited. We thus evaluated the diagnostic performance of differential time to positivity (DTP) to diagnose CRC in neutropenic cancer patients with suspected CRC. Of the 35 patients enrolled, 15 (43%) with CRC (six definite and nine probable) and 17 (49%) with non-CRC were finally analyzed. Based on the receiver operating characteristic curve, the optimal cutoff value of DTP for diagnosing CRC was ≥1.45 hours with the sensitivity 80% (95% confidence interval [CI], 51-95) and specificity 100% (95% CI, 80-100), respectively.

AB - Methods for distinguishing catheter-related candidemia (CRC) from non-CRC before catheter removal remain limited. We thus evaluated the diagnostic performance of differential time to positivity (DTP) to diagnose CRC in neutropenic cancer patients with suspected CRC. Of the 35 patients enrolled, 15 (43%) with CRC (six definite and nine probable) and 17 (49%) with non-CRC were finally analyzed. Based on the receiver operating characteristic curve, the optimal cutoff value of DTP for diagnosing CRC was ≥1.45 hours with the sensitivity 80% (95% confidence interval [CI], 51-95) and specificity 100% (95% CI, 80-100), respectively.

KW - candidemia

KW - catheter

KW - diagnosis

KW - differential time to positivity

KW - neutropenia

UR - https://www.scopus.com/pages/publications/85077403491

U2 - 10.1093/mmy/myz028

DO - 10.1093/mmy/myz028

M3 - Article

C2 - 30927433

AN - SCOPUS:85077403491

SN - 1369-3786

VL - 58

SP - 137

EP - 140

JO - Medical Mycology

JF - Medical Mycology

IS - 1

ER -

Diagnostic usefulness of differential time to positivity in neutropenic cancer patients with suspected catheter-related candidemia

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this