Disposable electrochemical sensors based on reduced graphene oxide/polyaniline/poly(alizarin red S)-modified integrated carbon electrodes for the detection of ciprofloxacin in milk

Mari Elancheziyan, Sooyeon Lee, Tae Hyun Yoon, Manisha Singh, Dogyeong Lee, Keehoon Won

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

An electrochemical sensor based on an electroactive nanocomposite was designed for the first time consisting of electrochemically reduced graphene oxide (ERGO), polyaniline (PANI), and poly(alizarin red S) (PARS) for ciprofloxacin (CIPF) detection. The ERGO/PANI/PARS-modified screen-printed carbon electrode (SPCE) was constructed through a three-step electrochemical protocol and characterized using FTIR, UV–visible spectroscopy, FESEM, CV, LSV, and EIS. The new electrochemical CIPF sensor demonstrated a low detection limit of 0.0021 μM, a broad linear range of 0.01 to 69.8 μM, a high sensitivity of 5.09 μA/μM/cm2, and reasonable selectivity and reproducibility. Moreover, the ERGO/PANI/PARS/SPCE was successfully utilized to determine CIPF in milk with good recoveries and relative standard deviation (< 5%), which were close to those with HPLC analysis. Graphical Abstract: (Figure presented.)

Original languageEnglish
Article number507
JournalMicrochimica Acta
Volume191
Issue number9
DOIs
StatePublished - Sep 2024

Keywords

  • Ciprofloxacin
  • Electrochemical sensor
  • Electrochemically reduced graphene oxide
  • Linear scan voltammetry
  • Poly(alizarin red S)
  • Polyaniline

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