TY - JOUR
T1 - Disposable electrochemical sensors based on reduced graphene oxide/polyaniline/poly(alizarin red S)-modified integrated carbon electrodes for the detection of ciprofloxacin in milk
AU - Elancheziyan, Mari
AU - Lee, Sooyeon
AU - Yoon, Tae Hyun
AU - Singh, Manisha
AU - Lee, Dogyeong
AU - Won, Keehoon
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature 2024.
PY - 2024/9
Y1 - 2024/9
N2 - An electrochemical sensor based on an electroactive nanocomposite was designed for the first time consisting of electrochemically reduced graphene oxide (ERGO), polyaniline (PANI), and poly(alizarin red S) (PARS) for ciprofloxacin (CIPF) detection. The ERGO/PANI/PARS-modified screen-printed carbon electrode (SPCE) was constructed through a three-step electrochemical protocol and characterized using FTIR, UV–visible spectroscopy, FESEM, CV, LSV, and EIS. The new electrochemical CIPF sensor demonstrated a low detection limit of 0.0021 μM, a broad linear range of 0.01 to 69.8 μM, a high sensitivity of 5.09 μA/μM/cm2, and reasonable selectivity and reproducibility. Moreover, the ERGO/PANI/PARS/SPCE was successfully utilized to determine CIPF in milk with good recoveries and relative standard deviation (< 5%), which were close to those with HPLC analysis. Graphical Abstract: (Figure presented.)
AB - An electrochemical sensor based on an electroactive nanocomposite was designed for the first time consisting of electrochemically reduced graphene oxide (ERGO), polyaniline (PANI), and poly(alizarin red S) (PARS) for ciprofloxacin (CIPF) detection. The ERGO/PANI/PARS-modified screen-printed carbon electrode (SPCE) was constructed through a three-step electrochemical protocol and characterized using FTIR, UV–visible spectroscopy, FESEM, CV, LSV, and EIS. The new electrochemical CIPF sensor demonstrated a low detection limit of 0.0021 μM, a broad linear range of 0.01 to 69.8 μM, a high sensitivity of 5.09 μA/μM/cm2, and reasonable selectivity and reproducibility. Moreover, the ERGO/PANI/PARS/SPCE was successfully utilized to determine CIPF in milk with good recoveries and relative standard deviation (< 5%), which were close to those with HPLC analysis. Graphical Abstract: (Figure presented.)
KW - Ciprofloxacin
KW - Electrochemical sensor
KW - Electrochemically reduced graphene oxide
KW - Linear scan voltammetry
KW - Poly(alizarin red S)
KW - Polyaniline
UR - http://www.scopus.com/inward/record.url?scp=85200441045&partnerID=8YFLogxK
U2 - 10.1007/s00604-024-06578-9
DO - 10.1007/s00604-024-06578-9
M3 - Article
C2 - 39098931
AN - SCOPUS:85200441045
SN - 0026-3672
VL - 191
JO - Microchimica Acta
JF - Microchimica Acta
IS - 9
M1 - 507
ER -