TY - JOUR
T1 - Distribution of antibiotic resistance in urban watershed in Japan
AU - Ham, Young Sik
AU - Kobori, Hiromi
AU - Kang, Joo Hyon
AU - Matsuzaki, Takayuki
AU - Iino, Michiyo
AU - Nomura, Hayashi
PY - 2012/3
Y1 - 2012/3
N2 - Antibiotic-resistant E. coli concentrations showed large spatial and temporal variations, with greater concentrations observed in tributaries and downstream than in the upstream and midstream. Twenty percent of the geometric mean concentrations of antibiotic-resistant E. coli in the Tama River basin (Japan) exceeded the maximum acceptable concentration of indicator E. coli established by the USEPA. The indicator E. coli concentrations were positively correlated with those of antibiotic-resistant E. coli and multiple-antibiotic- resistant E. coli (resistance to more than two kinds of antibiotics), respectively, but not the detection rate of antibiotic-resistant E. coli, implying that use of antibiotic-resistant E. coli concentration rather than the detection rate can be a better approach for water quality assessment. Multiple-antibiotic-resistant E. coli is a useful indicator for estimating the resistance diffusion, water quality degradation and public health risk potential. This assessment provides beneficial information for setting national regulatory or environmental standards and managing integrated watershed areas.
AB - Antibiotic-resistant E. coli concentrations showed large spatial and temporal variations, with greater concentrations observed in tributaries and downstream than in the upstream and midstream. Twenty percent of the geometric mean concentrations of antibiotic-resistant E. coli in the Tama River basin (Japan) exceeded the maximum acceptable concentration of indicator E. coli established by the USEPA. The indicator E. coli concentrations were positively correlated with those of antibiotic-resistant E. coli and multiple-antibiotic- resistant E. coli (resistance to more than two kinds of antibiotics), respectively, but not the detection rate of antibiotic-resistant E. coli, implying that use of antibiotic-resistant E. coli concentration rather than the detection rate can be a better approach for water quality assessment. Multiple-antibiotic-resistant E. coli is a useful indicator for estimating the resistance diffusion, water quality degradation and public health risk potential. This assessment provides beneficial information for setting national regulatory or environmental standards and managing integrated watershed areas.
KW - Antibiotic-resistant Escherichia coli
KW - Resistance diffusion
KW - Spatiotemporal variation
KW - Urban watershed
KW - Water quality assessment
UR - http://www.scopus.com/inward/record.url?scp=82655176594&partnerID=8YFLogxK
U2 - 10.1016/j.envpol.2011.11.002
DO - 10.1016/j.envpol.2011.11.002
M3 - Article
C2 - 22243853
AN - SCOPUS:82655176594
SN - 0269-7491
VL - 162
SP - 98
EP - 103
JO - Environmental Pollution
JF - Environmental Pollution
ER -