Elastic fiber staining and cytokeratin 15 expression pattern in trichoepithelioma and basal cell carcinoma

Chong Won Choi, Hyun Sun Park, Yeon Kyung Kim, Seung Ho Lee, Kwang Hyun Cho

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Trichoepithelioma (TE) is a benign neoplasm of the skin that resembles basal cell carcinoma (BCC) in its clinical and histological features. In this study, we evaluate the usefulness of elastic fiber staining and cytokeratin 15 expression pattern in terms of distinguishing TE from BCC. Eleven TE and 17 BCC were examined histochemically and immunohistochemically. It was found that BCC contain more elastic fiber than TE, and that more TE show peripheral localization than BCC in cytokeratin 15 expression patterns. The present study shows that elastic fiber staining and cytokeratin 15 expression pattern may aid the differentiation of TE from BCC.

Original languageEnglish
Pages (from-to)499-502
Number of pages4
JournalJournal of Dermatology
Volume35
Issue number8
DOIs
StatePublished - Sep 2008

Keywords

  • Basal cell carcinoma
  • Cytokeratin 15
  • Elastic fiber
  • Trichoepithelioma

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