Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter

Arivalagan Pugazhendhi; Sridevi Dhanarani; Congeevaram Shankar; Piruthiviraj Prakash; Kuppusamy Ranganathan; Rijuta Ganesh Saratale; Kaliannan Thamaraiselvi

doi:10.1016/j.micpath.2017.07.003

Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter

Arivalagan Pugazhendhi
, Sridevi Dhanarani
, Congeevaram Shankar
, Piruthiviraj Prakash
, Kuppusamy Ranganathan
, Rijuta Ganesh Saratale
, Kaliannan Thamaraiselvi

Research Institute of Integrative Life Sciences

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

The present study is aimed to assess the role of glutathione S-transferase (GST) in antibiotic resistance among the bacteria isolated from the poultry litter and to identify the effect of GST to reduce the antimicrobial activity of antibiotics. Induction of various antibiotics to Staphylococcus, Streptococcus and Micrococcus sp. isolated from the poultry litter showed that the activity of GST was three to four folds higher than those of control. Analysis of the isozyme pattern of GST revealed that variation in the expression may be due to antibiotic resistance. The results concluded that GST might play an important role in the protection against the toxic effect of the antimicrobial agents which leads bacteria to become resistant to antibiotics.

Original language	English
Pages (from-to)	285-290
Number of pages	6
Journal	Microbial Pathogenesis
Volume	110
DOIs	https://doi.org/10.1016/j.micpath.2017.07.003
State	Published - Sep 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Antibiotics
Glutathione S-transferase (GST)
Isozyme
Poultry litter
Resistant bacteria

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10.1016/j.micpath.2017.07.003

Cite this

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title = "Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter",

abstract = "The present study is aimed to assess the role of glutathione S-transferase (GST) in antibiotic resistance among the bacteria isolated from the poultry litter and to identify the effect of GST to reduce the antimicrobial activity of antibiotics. Induction of various antibiotics to Staphylococcus, Streptococcus and Micrococcus sp. isolated from the poultry litter showed that the activity of GST was three to four folds higher than those of control. Analysis of the isozyme pattern of GST revealed that variation in the expression may be due to antibiotic resistance. The results concluded that GST might play an important role in the protection against the toxic effect of the antimicrobial agents which leads bacteria to become resistant to antibiotics.",

keywords = "Antibiotics, Glutathione S-transferase (GST), Isozyme, Poultry litter, Resistant bacteria",

author = "Arivalagan Pugazhendhi and Sridevi Dhanarani and Congeevaram Shankar and Piruthiviraj Prakash and Kuppusamy Ranganathan and Saratale, \{Rijuta Ganesh\} and Kaliannan Thamaraiselvi",

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year = "2017",

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doi = "10.1016/j.micpath.2017.07.003",

language = "English",

volume = "110",

pages = "285--290",

journal = "Microbial Pathogenesis",

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T1 - Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter

AU - Pugazhendhi, Arivalagan

AU - Dhanarani, Sridevi

AU - Shankar, Congeevaram

AU - Prakash, Piruthiviraj

AU - Ranganathan, Kuppusamy

AU - Saratale, Rijuta Ganesh

AU - Thamaraiselvi, Kaliannan

PY - 2017/9

Y1 - 2017/9

N2 - The present study is aimed to assess the role of glutathione S-transferase (GST) in antibiotic resistance among the bacteria isolated from the poultry litter and to identify the effect of GST to reduce the antimicrobial activity of antibiotics. Induction of various antibiotics to Staphylococcus, Streptococcus and Micrococcus sp. isolated from the poultry litter showed that the activity of GST was three to four folds higher than those of control. Analysis of the isozyme pattern of GST revealed that variation in the expression may be due to antibiotic resistance. The results concluded that GST might play an important role in the protection against the toxic effect of the antimicrobial agents which leads bacteria to become resistant to antibiotics.

AB - The present study is aimed to assess the role of glutathione S-transferase (GST) in antibiotic resistance among the bacteria isolated from the poultry litter and to identify the effect of GST to reduce the antimicrobial activity of antibiotics. Induction of various antibiotics to Staphylococcus, Streptococcus and Micrococcus sp. isolated from the poultry litter showed that the activity of GST was three to four folds higher than those of control. Analysis of the isozyme pattern of GST revealed that variation in the expression may be due to antibiotic resistance. The results concluded that GST might play an important role in the protection against the toxic effect of the antimicrobial agents which leads bacteria to become resistant to antibiotics.

KW - Antibiotics

KW - Glutathione S-transferase (GST)

KW - Isozyme

KW - Poultry litter

KW - Resistant bacteria

UR - https://www.scopus.com/pages/publications/85022330897

U2 - 10.1016/j.micpath.2017.07.003

DO - 10.1016/j.micpath.2017.07.003

M3 - Article

C2 - 28687323

AN - SCOPUS:85022330897

SN - 0882-4010

VL - 110

SP - 285

EP - 290

JO - Microbial Pathogenesis

JF - Microbial Pathogenesis

ER -

Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter

Abstract

UN SDGs

Keywords

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