@inproceedings{f1dd7a73ce0e453988b68b26371a6a2f,
title = "Engineering a 3D neural circuit, blood-brain barrier, and myelination in microfluidic 96 well plate",
abstract = "Microfluidic devices based on polydimethylsiloxane (PDMS) facilitate research in the fields of neuroscience. However, wider applications of these platforms to high-content or high-throughput drug screening are still challenging due to inherent material properties and lack of standardized manufactural devices. Here, we present an injection molded three-dimensional (3D) neuron culture platform with 96-well plate format (Neuro-IMPACT) that can recapitulate elements of the nervous system such as neural circuit, blood-brain barrier, and myelination. A standardized in vitro platform with a new patterning method allow high-throughput experiments. The platform enables not only long-term 3D neuron culture, but also co-culture to assist neuroscience research.",
keywords = "3D culture platform, High-throughput screening, Microfluidics, Nervous system, Organ-on-a-chip",
author = "Lee, {Seung Ryeol} and Sujin Hyung and Seokyoung Bang and Jeon, {Noo Li}",
note = "Publisher Copyright: {\textcopyright} 2019 CBMS-0001.; 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 ; Conference date: 27-10-2019 Through 31-10-2019",
year = "2019",
language = "English",
series = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
publisher = "Chemical and Biological Microsystems Society",
pages = "450--451",
booktitle = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
}