Ethnic variation of cord plasma apolipoprotein levels in relation to coronary risk level: A study in three ethnic groups of Singapore

P. S. Low, N. Saha, J. S.H. Tay, S. Hong

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14 Scopus citations

Abstract

In multiracial Singapore, the prevalence of coronary artery disease is highest in ethnic Indian and lowest in ethnic Chinese populations. Since susceptibility to coronary artery disease is closely associated with plasma lipid traits, we studied the cord blood lipid and apolipoprotein profiles of the three ethnic groups in Singapore to determine if ethnic differences in lipid profile are present at birth. The high-risk lipid traits of high LDL-cholesterol, triglycerides and apo B, low HDL-cholesterol and apo A-I were found to be highest in ethnic Indian and lowest in ethnic Chinese populations. This difference was concordant with the relative coronary mortality rates for their respective adult populations in Singapore.

Original languageEnglish
Pages (from-to)1476-1482
Number of pages7
JournalActa Paediatrica, International Journal of Paediatrics
Volume85
Issue number12
DOIs
StatePublished - 1996

Keywords

  • Apo A-I
  • apo B
  • Asian
  • HDL-cholesterol
  • LDL-cholesterol
  • newborn

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