Frosta®: A new technology for making fast-melting tablets

Seong Hoon Jeong, Yourong Fu, Kinam Park

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

The fast-melting tablet (FMT) technology, which is known to be one of the most innovated methods in oral drug delivery systems, is a rapidly growing area of drug delivery. The initial success of the FMT formulation led to the development of various technologies. These technologies, however, still have some limitations. Recently, a new technology called Frosta® (Akina) was developed for making FMTs. The Frosta technology utilises the conventional wet granulation process and tablet press for cost-effective production of tablets. The Frosta tablets are mechanically strong with friability of < 1% and are stable in accelerated stability conditions when packaged into a bottle container. They are robust enough to be packaged in multi-tablet vials. Conventional rotary tablet presses can be used for the production of the tablets and no other special instruments are required. Thus, the cost of making FMTs is lower than that of other existing technologies. Depending on the size, Frosta tablets can melt in < 10 s after placing them in the oral cavity for easy swallowing. The Frosta technology is ideal for wide application of FMTs technology to various drug and nutritional formulations.

Original languageEnglish
Pages (from-to)1107-1116
Number of pages10
JournalExpert Opinion on Drug Delivery
Volume2
Issue number6
DOIs
StatePublished - Nov 2005

Keywords

  • Fast-melting tablet
  • Frosta®
  • Highly plastic granules
  • Highly porous structure
  • Plastic material
  • Water-penetration enhancer
  • Wet binder

Fingerprint

Dive into the research topics of 'Frosta®: A new technology for making fast-melting tablets'. Together they form a unique fingerprint.

Cite this