TY - JOUR
T1 - GeneCo
T2 - A visualized comparative genomic method to analyze multiple genome structures
AU - Jung, Jaehee
AU - Kim, Jong Im
AU - Yi, Gangman
N1 - Publisher Copyright:
© 2019 The Author(s) . Published by Oxford University Press.
PY - 2019/12/15
Y1 - 2019/12/15
N2 - Summary: In comparative and evolutionary genomics, a detailed comparison of common features between organisms is essential to evaluate genetic distance. However, identifying differences in matched and mismatched genes among multiple genomes is difficult using current comparative genomic approaches due to complicated methodologies or the generation of meager information from obtained results. This study describes a visualized software tool, geneCo (gene Comparison), for comparing genome structure and gene arrangements between various organisms. User data are aligned, gene information is recognized, and genome structures are compared based on user-defined GenBank files. Information regarding inversion, gain, loss, duplication and gene rearrangement among multiple organisms being compared is provided by geneCo, which uses a web-based interface that users can easily access without any need to consider the computational environment.
AB - Summary: In comparative and evolutionary genomics, a detailed comparison of common features between organisms is essential to evaluate genetic distance. However, identifying differences in matched and mismatched genes among multiple genomes is difficult using current comparative genomic approaches due to complicated methodologies or the generation of meager information from obtained results. This study describes a visualized software tool, geneCo (gene Comparison), for comparing genome structure and gene arrangements between various organisms. User data are aligned, gene information is recognized, and genome structures are compared based on user-defined GenBank files. Information regarding inversion, gain, loss, duplication and gene rearrangement among multiple organisms being compared is provided by geneCo, which uses a web-based interface that users can easily access without any need to consider the computational environment.
UR - http://www.scopus.com/inward/record.url?scp=85077770117&partnerID=8YFLogxK
U2 - 10.1093/bioinformatics/btz596
DO - 10.1093/bioinformatics/btz596
M3 - Article
C2 - 31350879
AN - SCOPUS:85077770117
SN - 1367-4803
VL - 35
SP - 5303
EP - 5305
JO - Bioinformatics
JF - Bioinformatics
IS - 24
ER -