TY - JOUR
T1 - Geriatric assessment using the G8 to predict postoperative complications in patients undergoing major uro-oncologic surgery
T2 - Comparison with the Charlson Comorbidity Index
AU - Park, Dae Hyoung
AU - Yoo, Sanghyun
AU - Do, Minh Tung
AU - Yoon, Hyun Sik
AU - Jung, Gyoohwan
AU - Suh, Jungyo
AU - Yuk, Hyeong Dong
AU - Ku, Ja Hyeon
AU - Kwak, Cheol
AU - Kim, Hyeon Hoe
AU - Jeong, Chang Wook
N1 - Publisher Copyright:
© 2022
PY - 2022/5
Y1 - 2022/5
N2 - Objective: To evaluate the ability of the G8 assessment to predict postoperative complications in older adults undergoing major uro-oncologic surgery in comparison with the Charlson Comorbidity Index (CCI). Materials and methods: The study included patients ≥65 years old who underwent major uro-oncologic surgery between December 2017 and December 2019 and were enrolled in the Seoul National University Prospectively Enrolled Registry for Genitourinary Cancer (SUPER-GUC). Odds ratio (OR) smoothing was used to visualize risk according to G8 scores. Chi-square tests were used to compare postoperative complication rates according to G8 score or CCI category. Results: A total of 657 patients undergoing radical prostatectomies (n = 372, 56.6%), partial/radical nephrectomies (n = 149, 22.7%), radical cystectomies (n = 76, 11.6%), and nephroureterectomies (n = 60, 9.1%) were included. Complication rates did not significantly differ between patients with CCI scores ≥1 and those with CCI scores of 0 (15.0% vs. 12.4%, p = 0.34). However, the complication rate was significantly higher in patients with G8 scores ≤14 than in those with G8 scores >14 (18.1% vs. 10.5%, p = 0.005). When the OR smoothing curve was used to divide patients into three groups based on G8 scores of <10, 10–14, and > 14, we observed significant differences in complication rates among the groups (37.5% vs. 16.9%. vs. 10.5%; p = 0.001). Conclusion: The G8 can aid in predicting postoperative complications in patients ≥65 years old. Comprehensive geriatric assessment is warranted in patients with G8 scores ≤14 prior to major uro-oncologic surgery. Older patients with G8 scores <10 should be counseled regarding the very high risk of surgery.
AB - Objective: To evaluate the ability of the G8 assessment to predict postoperative complications in older adults undergoing major uro-oncologic surgery in comparison with the Charlson Comorbidity Index (CCI). Materials and methods: The study included patients ≥65 years old who underwent major uro-oncologic surgery between December 2017 and December 2019 and were enrolled in the Seoul National University Prospectively Enrolled Registry for Genitourinary Cancer (SUPER-GUC). Odds ratio (OR) smoothing was used to visualize risk according to G8 scores. Chi-square tests were used to compare postoperative complication rates according to G8 score or CCI category. Results: A total of 657 patients undergoing radical prostatectomies (n = 372, 56.6%), partial/radical nephrectomies (n = 149, 22.7%), radical cystectomies (n = 76, 11.6%), and nephroureterectomies (n = 60, 9.1%) were included. Complication rates did not significantly differ between patients with CCI scores ≥1 and those with CCI scores of 0 (15.0% vs. 12.4%, p = 0.34). However, the complication rate was significantly higher in patients with G8 scores ≤14 than in those with G8 scores >14 (18.1% vs. 10.5%, p = 0.005). When the OR smoothing curve was used to divide patients into three groups based on G8 scores of <10, 10–14, and > 14, we observed significant differences in complication rates among the groups (37.5% vs. 16.9%. vs. 10.5%; p = 0.001). Conclusion: The G8 can aid in predicting postoperative complications in patients ≥65 years old. Comprehensive geriatric assessment is warranted in patients with G8 scores ≤14 prior to major uro-oncologic surgery. Older patients with G8 scores <10 should be counseled regarding the very high risk of surgery.
KW - Charlson Comorbidity Index
KW - Comprehensive geriatric assessment
KW - G8
KW - Geriatric oncology
KW - Nephrectomy
KW - Postoperative complications
KW - Questionnaire
KW - Radical cystectomy
KW - Radical nephroureterectomy
KW - Radical prostatectomy
UR - http://www.scopus.com/inward/record.url?scp=85124246423&partnerID=8YFLogxK
U2 - 10.1016/j.jgo.2022.01.011
DO - 10.1016/j.jgo.2022.01.011
M3 - Article
C2 - 35123918
AN - SCOPUS:85124246423
SN - 1879-4068
VL - 13
SP - 426
EP - 431
JO - Journal of Geriatric Oncology
JF - Journal of Geriatric Oncology
IS - 4
ER -