Growth factors and signaling pathways in the chondrogenic differentiation of mesenchymal stem cells

T. S. Shanmugarajan, Byung Soo Kim, Haeshin Lee, Gun Il Im

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Mesenchymal stem cells (MSCs) are multipotent progenitor cells that can differentiate into the several lineages. MSC has drawn an enormous attention because of the potential for use in tissue engineering and regenerative medicine. Several growth factors and signaling mechanisms strongly influence chondrogenic differentiation of MSCs. In this review, we summarized the roles of these growth factors and signaling mechanisms involved in chondrogenic differentiation of MSCs.

Original languageEnglish
Pages (from-to)292-299
Number of pages8
JournalTissue Engineering and Regenerative Medicine
Volume8
Issue number3
StatePublished - May 2011

Keywords

  • Cell differentiation
  • Chondrogenesis
  • Growth factors
  • Mesenchymal stem cells

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