Identification of phenolic constituents and antioxidant activity of aloe barbadensis flower extracts

Trishna Debnath; Mithun Ghosh; Young Min Lee; Narayan Chandra Deb Nath; Kwang Geun Lee; Beong Ou Lim

doi:10.1080/09540105.2017.1358254

Identification of phenolic constituents and antioxidant activity of aloe barbadensis flower extracts

Trishna Debnath, Mithun Ghosh, Young Min Lee, Narayan Chandra Deb Nath, Kwang Geun Lee, Beong Ou Lim

Department of Food Science & Biotechnology

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Aloe vera (Aloe barbadensis Miller) has been used as topical and oral therapeutic. This research highlights the phenolic constituents’ profile and antioxidant activity of 70% ethanol extracts of Aloe vera flower for the first time. The ethanol-based extracts showed the inhibition for linoleic acid oxidation and free radical-induced DNA damage. Among about 11 phenolic constituents of the extract, identified by using high performance liquid chromatography (HPLC), the content of vanillic acid was highest, corresponding to strong antioxidant activities of the extract. The extracts elevated superoxide dismutase, catalase, and glutathione peroxidase enzymes activities in the liver tissue of hydrogen peroxide-treated BALB/c mice. The radical-scavenging activities of the extracts were well-correlated to the total phenolic content. Therefore, Aloe bardadensis flower might be an effective source of natural antioxidant.

Original language	English
Pages (from-to)	27-38
Number of pages	12
Journal	Food and Agricultural Immunology
Volume	29
Issue number	1
DOIs	https://doi.org/10.1080/09540105.2017.1358254
State	Published - 22 Jul 2018

Keywords

Aloe vera flower
Antioxidant enzymes
Electron spin resonance (ESR)
Phenolic compound

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10.1080/09540105.2017.1358254

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title = "Identification of phenolic constituents and antioxidant activity of aloe barbadensis flower extracts",

abstract = "Aloe vera (Aloe barbadensis Miller) has been used as topical and oral therapeutic. This research highlights the phenolic constituents{\textquoteright} profile and antioxidant activity of 70% ethanol extracts of Aloe vera flower for the first time. The ethanol-based extracts showed the inhibition for linoleic acid oxidation and free radical-induced DNA damage. Among about 11 phenolic constituents of the extract, identified by using high performance liquid chromatography (HPLC), the content of vanillic acid was highest, corresponding to strong antioxidant activities of the extract. The extracts elevated superoxide dismutase, catalase, and glutathione peroxidase enzymes activities in the liver tissue of hydrogen peroxide-treated BALB/c mice. The radical-scavenging activities of the extracts were well-correlated to the total phenolic content. Therefore, Aloe bardadensis flower might be an effective source of natural antioxidant.",

keywords = "Aloe vera flower, Antioxidant enzymes, Electron spin resonance (ESR), Phenolic compound",

author = "Trishna Debnath and Mithun Ghosh and Lee, {Young Min} and Nath, {Narayan Chandra Deb} and Lee, {Kwang Geun} and Lim, {Beong Ou}",

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AU - Debnath, Trishna

AU - Ghosh, Mithun

AU - Lee, Young Min

AU - Nath, Narayan Chandra Deb

AU - Lee, Kwang Geun

AU - Lim, Beong Ou

PY - 2018/7/22

Y1 - 2018/7/22

N2 - Aloe vera (Aloe barbadensis Miller) has been used as topical and oral therapeutic. This research highlights the phenolic constituents’ profile and antioxidant activity of 70% ethanol extracts of Aloe vera flower for the first time. The ethanol-based extracts showed the inhibition for linoleic acid oxidation and free radical-induced DNA damage. Among about 11 phenolic constituents of the extract, identified by using high performance liquid chromatography (HPLC), the content of vanillic acid was highest, corresponding to strong antioxidant activities of the extract. The extracts elevated superoxide dismutase, catalase, and glutathione peroxidase enzymes activities in the liver tissue of hydrogen peroxide-treated BALB/c mice. The radical-scavenging activities of the extracts were well-correlated to the total phenolic content. Therefore, Aloe bardadensis flower might be an effective source of natural antioxidant.

AB - Aloe vera (Aloe barbadensis Miller) has been used as topical and oral therapeutic. This research highlights the phenolic constituents’ profile and antioxidant activity of 70% ethanol extracts of Aloe vera flower for the first time. The ethanol-based extracts showed the inhibition for linoleic acid oxidation and free radical-induced DNA damage. Among about 11 phenolic constituents of the extract, identified by using high performance liquid chromatography (HPLC), the content of vanillic acid was highest, corresponding to strong antioxidant activities of the extract. The extracts elevated superoxide dismutase, catalase, and glutathione peroxidase enzymes activities in the liver tissue of hydrogen peroxide-treated BALB/c mice. The radical-scavenging activities of the extracts were well-correlated to the total phenolic content. Therefore, Aloe bardadensis flower might be an effective source of natural antioxidant.

KW - Aloe vera flower

KW - Antioxidant enzymes

KW - Electron spin resonance (ESR)

KW - Phenolic compound

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Identification of phenolic constituents and antioxidant activity of aloe barbadensis flower extracts

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Keywords

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