TY - JOUR
T1 - Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis
T2 - The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Imaging
AU - Park, Jun Kyeong
AU - Lee, Eun Ja
AU - Kim, Kwang Ki
N1 - Publisher Copyright:
Copyrights © 2021 The Korean Society of Radiology
PY - 2022
Y1 - 2022
N2 - Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a common autoimmune encephalitis that is noted to be a severe but treatable disease entity. Patients with anti-NMDAR encephalitis often develop psychotic symptoms, including delusions, hallucinations, and paranoia, as well as memory impairment and persistent loss of attention. However, MRI findings in such patients show no abnormalities in most cases. Although typical brain abnormality features, known as T2 hyperintensities, involve the brain parenchyma and contrast enhancement at the cerebral cortex or overlying meninges, isolated leptomeningeal enhancement has been rarely reported in anti-NMDAR encephalitis. Herein, we report a patient with anti-NMDAR encephalitis who presented with isolated leptomeningeal enhancement, additionally showing the diagnostic value of contrast-enhanced fluid-attenuated inversion recovery imaging.
AB - Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a common autoimmune encephalitis that is noted to be a severe but treatable disease entity. Patients with anti-NMDAR encephalitis often develop psychotic symptoms, including delusions, hallucinations, and paranoia, as well as memory impairment and persistent loss of attention. However, MRI findings in such patients show no abnormalities in most cases. Although typical brain abnormality features, known as T2 hyperintensities, involve the brain parenchyma and contrast enhancement at the cerebral cortex or overlying meninges, isolated leptomeningeal enhancement has been rarely reported in anti-NMDAR encephalitis. Herein, we report a patient with anti-NMDAR encephalitis who presented with isolated leptomeningeal enhancement, additionally showing the diagnostic value of contrast-enhanced fluid-attenuated inversion recovery imaging.
KW - Anti-NMDA Receptor Encephalitis
KW - Brain
KW - Magnetic Resonance Imaging
UR - http://www.scopus.com/inward/record.url?scp=85124011767&partnerID=8YFLogxK
U2 - 10.3348/jksr.2021.0098
DO - 10.3348/jksr.2021.0098
M3 - Article
AN - SCOPUS:85124011767
SN - 1738-2637
VL - 83
JO - Journal of the Korean Society of Radiology (South Korea)
JF - Journal of the Korean Society of Radiology (South Korea)
M1 - 98
ER -