Magnetic resonance imaging of pachymeningeal enhancement in Vogt-Koyanagi-Harada disease

Hyun Jeong Han, Hye Yun Kim, Jong Ho Park, Eun Ja Lee, Do Gyun Kim, Dong Ick Shin

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Vogt-Koyanagi-Harada (VKH) disease is a systemic disease consisting of bilateral granulomatous panuveitis combined with cutaneous and neurologic manifestations. However, there have been few reports of brain magnetic resonance imaging (MRI) in VKH disease. A 54-year-old Korean woman presented with severe periorbital pain, blurred vision and meningismus. Ophthalmologic examination disclosed bilateral optic disc edema with peripapillary nerve fiber hemorrhages. Lumbar puncture revealed monocytic pleocytosis. After a diagnosis of VKH disease was made, the patient was treated with high-dose corticosteroid. Brain MRI showed diffusely thickened posterior ocular walls with retinal detachment and perineural infiltrative changes along the optic nerves and adjacent pachymeningeal enhancement of the anterior temporal lobes bilaterally. We report a case of VKH disease with panuveitis and meningeal involvement of the anterior temporal lobe detected by brain MRI.

Original languageEnglish
Pages (from-to)785-788
Number of pages4
JournalNeurological Sciences
Volume31
Issue number6
DOIs
StatePublished - Dec 2010

Keywords

  • Magnetic resonance imaging
  • Monocytic pleocytosis
  • Optic disc edema
  • Vogt-Koyanagi-Harada disease

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