Major Bioactive Compounds from Java Plum Seeds: An Investigation of Its Extraction Procedures and Clinical Effects

Gitishree Das, Rajat Nath, Anupam Das Talukdar, Duygu Ağagündüz, Birsen Yilmaz, Raffaele Capasso, Han Seung Shin, Jayanta Kumar Patra

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Java plum is widely recognized as a plant with valuable medicinal properties, originating from Indonesia and India and distributed globally in the tropic and sub-tropic regions of the world. The plant is rich in alkaloids, flavonoids, phenyl propanoids, terpenes, tannins, and lipids. The phytoconstituents of the plant seeds possess various vital pharmacological activities and clinical effects including their antidiabetic potential. The bioactive phytoconstituents of Java plum seeds include jambosine, gallic acid, quercetin, β-sitosterol, ferulic acid, guaiacol, resorcinol, p-coumaric acid, corilagin, ellagic acid, catechin, epicatechin, tannic acid, 4,6 hexahydroxydiphenoyl glucose, 3,6-hexahydroxy diphenoylglucose, 1-galloylglucose, and 3-galloylglucose. Considering all the potential beneficial effects of the major bioactive compounds present in the Jamun seeds, in the current investigation, the specific clinical effects and the mechanism of action for the major bioactive compounds along with the extraction procedures are discussed.

Original languageEnglish
Article number1214
JournalPlants
Volume12
Issue number6
DOIs
StatePublished - Mar 2023

Keywords

  • bioactive compounds
  • clinical effects
  • diabetes
  • extraction
  • jambosine
  • java plum seeds
  • mode of action

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