TY - JOUR
T1 - Major Bioactive Compounds from Java Plum Seeds
T2 - An Investigation of Its Extraction Procedures and Clinical Effects
AU - Das, Gitishree
AU - Nath, Rajat
AU - Das Talukdar, Anupam
AU - Ağagündüz, Duygu
AU - Yilmaz, Birsen
AU - Capasso, Raffaele
AU - Shin, Han Seung
AU - Patra, Jayanta Kumar
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/3
Y1 - 2023/3
N2 - Java plum is widely recognized as a plant with valuable medicinal properties, originating from Indonesia and India and distributed globally in the tropic and sub-tropic regions of the world. The plant is rich in alkaloids, flavonoids, phenyl propanoids, terpenes, tannins, and lipids. The phytoconstituents of the plant seeds possess various vital pharmacological activities and clinical effects including their antidiabetic potential. The bioactive phytoconstituents of Java plum seeds include jambosine, gallic acid, quercetin, β-sitosterol, ferulic acid, guaiacol, resorcinol, p-coumaric acid, corilagin, ellagic acid, catechin, epicatechin, tannic acid, 4,6 hexahydroxydiphenoyl glucose, 3,6-hexahydroxy diphenoylglucose, 1-galloylglucose, and 3-galloylglucose. Considering all the potential beneficial effects of the major bioactive compounds present in the Jamun seeds, in the current investigation, the specific clinical effects and the mechanism of action for the major bioactive compounds along with the extraction procedures are discussed.
AB - Java plum is widely recognized as a plant with valuable medicinal properties, originating from Indonesia and India and distributed globally in the tropic and sub-tropic regions of the world. The plant is rich in alkaloids, flavonoids, phenyl propanoids, terpenes, tannins, and lipids. The phytoconstituents of the plant seeds possess various vital pharmacological activities and clinical effects including their antidiabetic potential. The bioactive phytoconstituents of Java plum seeds include jambosine, gallic acid, quercetin, β-sitosterol, ferulic acid, guaiacol, resorcinol, p-coumaric acid, corilagin, ellagic acid, catechin, epicatechin, tannic acid, 4,6 hexahydroxydiphenoyl glucose, 3,6-hexahydroxy diphenoylglucose, 1-galloylglucose, and 3-galloylglucose. Considering all the potential beneficial effects of the major bioactive compounds present in the Jamun seeds, in the current investigation, the specific clinical effects and the mechanism of action for the major bioactive compounds along with the extraction procedures are discussed.
KW - bioactive compounds
KW - clinical effects
KW - diabetes
KW - extraction
KW - jambosine
KW - java plum seeds
KW - mode of action
UR - http://www.scopus.com/inward/record.url?scp=85151365194&partnerID=8YFLogxK
U2 - 10.3390/plants12061214
DO - 10.3390/plants12061214
M3 - Review article
AN - SCOPUS:85151365194
SN - 2223-7747
VL - 12
JO - Plants
JF - Plants
IS - 6
M1 - 1214
ER -