Manipulation of Thermoresponsive Polymers Using Biomolecules

Krishan Kumar, Reddicherla Umapathi, Sanjay Mor, Seyed Majid Ghoreishian, Jitendra N. Tiwari, Marzieh Ramezani Farani, Yun Suk Huh, Pannuru Venkatesu

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Thermoresponsive polymers (TRPs) have attracted considerable interest in the scientific community because of their potential applications in sensors, gels, drug delivery devices, biotechnology, and pharmacology. Certain biomolecules alter the phase transition behavior of TRPs by acting as external biological stimuli. Herein, we describe recently reported results and trends for TRP/biomolecule mixed systems in which biological stimuli modulate temperature-dependent polymer transitions and reviewed studies related to protein-polymer assembly formation, interactions, and temperature-dependent protein adsorption. Modifying polymer properties in response to biomolecules, which are inherently present in the human body, designs polymeric biomaterials with envisaged applications. We hope this review sheds light on scientific problems concerning biomolecule-polymer mixed systems and helps in designing next-generation “smart” polymers.

Original languageEnglish
Pages (from-to)3181-3200
Number of pages20
JournalACS Applied Polymer Materials
Volume5
Issue number5
DOIs
StatePublished - 12 May 2023

Keywords

  • biological stimuli
  • phase transition
  • polymer−biomolecules interactions
  • protein adsorption
  • thermoresponsive polymers

Fingerprint

Dive into the research topics of 'Manipulation of Thermoresponsive Polymers Using Biomolecules'. Together they form a unique fingerprint.

Cite this