TY - JOUR
T1 - Manipulation of Thermoresponsive Polymers Using Biomolecules
AU - Kumar, Krishan
AU - Umapathi, Reddicherla
AU - Mor, Sanjay
AU - Ghoreishian, Seyed Majid
AU - Tiwari, Jitendra N.
AU - Farani, Marzieh Ramezani
AU - Huh, Yun Suk
AU - Venkatesu, Pannuru
N1 - Publisher Copyright:
© 2023 American Chemical Society.
PY - 2023/5/12
Y1 - 2023/5/12
N2 - Thermoresponsive polymers (TRPs) have attracted considerable interest in the scientific community because of their potential applications in sensors, gels, drug delivery devices, biotechnology, and pharmacology. Certain biomolecules alter the phase transition behavior of TRPs by acting as external biological stimuli. Herein, we describe recently reported results and trends for TRP/biomolecule mixed systems in which biological stimuli modulate temperature-dependent polymer transitions and reviewed studies related to protein-polymer assembly formation, interactions, and temperature-dependent protein adsorption. Modifying polymer properties in response to biomolecules, which are inherently present in the human body, designs polymeric biomaterials with envisaged applications. We hope this review sheds light on scientific problems concerning biomolecule-polymer mixed systems and helps in designing next-generation “smart” polymers.
AB - Thermoresponsive polymers (TRPs) have attracted considerable interest in the scientific community because of their potential applications in sensors, gels, drug delivery devices, biotechnology, and pharmacology. Certain biomolecules alter the phase transition behavior of TRPs by acting as external biological stimuli. Herein, we describe recently reported results and trends for TRP/biomolecule mixed systems in which biological stimuli modulate temperature-dependent polymer transitions and reviewed studies related to protein-polymer assembly formation, interactions, and temperature-dependent protein adsorption. Modifying polymer properties in response to biomolecules, which are inherently present in the human body, designs polymeric biomaterials with envisaged applications. We hope this review sheds light on scientific problems concerning biomolecule-polymer mixed systems and helps in designing next-generation “smart” polymers.
KW - biological stimuli
KW - phase transition
KW - polymer−biomolecules interactions
KW - protein adsorption
KW - thermoresponsive polymers
UR - http://www.scopus.com/inward/record.url?scp=85156268099&partnerID=8YFLogxK
U2 - 10.1021/acsapm.2c02162
DO - 10.1021/acsapm.2c02162
M3 - Article
AN - SCOPUS:85156268099
SN - 2637-6105
VL - 5
SP - 3181
EP - 3200
JO - ACS Applied Polymer Materials
JF - ACS Applied Polymer Materials
IS - 5
ER -