Abstract
Pattern of events: A simple and flexible method has been developed for patterning cell adhesion ligands. Locally erasing self-assembled monolayers with tri(ethyleneglycol) groups on a gold substrate by using a MALDI-TOF MS nitrogen laser and filling the exposed gold surface with an alkanethiol presenting carboxylic acid groups enables subsequent immobilization of maleimide and a cell adhesion peptide, which can then recognize cells (see scheme).
Original language | English |
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Pages (from-to) | 3507-3511 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 19 |
DOIs | |
State | Published - 27 Apr 2009 |
Keywords
- Cell adhesion
- Fluorescence imaging
- Lithography
- Mass spectrometry
- Monolayers