Mild, simple, and efficient method for N-formylation of secondary amines via Reimer-Tiemann reaction

  • Lokesh A. Shastri
  • , Samundeeswari L. Shastri
  • , Chinna D. Bathula
  • , Mahantesha Basanagouda
  • , Manohar V. Kulkarni

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

A rapid and easy route for the N-formylation of secondary amines using chloroform and sodium ethoxide via dichlorocarbene by the Riemer-Tiemann reaction with excellent yield is reported.

Original languageEnglish
Pages (from-to)476-484
Number of pages9
JournalSynthetic Communications
Volume41
Issue number4
DOIs
StatePublished - Jan 2011

Keywords

  • Dichlorocarbene
  • N-formylation
  • Reimer-Tiemann
  • secondary amines
  • sodium ethoxide

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