@inbook{24e6d31c1ad148fbb7067e9908094e21,
title = "Monoclonal antibody-conjugated dendritic nanostructures for siRNA delivery",
abstract = "Small interfering RNA (siRNA) is a promising tool for gene therapy-based disease treatments. However, delivery of siRNA to the target cells requires a specific and reliable carrier system. Herein we describe a targeted carrier system that can deliver siRNA to cancer cells overexpressing the human epidermal growth factor 2 (HER2) receptor. Trastuzumab-conjugated poly(amido)amine dendrimers can be synthesized using the protocols described here.",
keywords = "Bioconjugation, Dendrimers, HER2 receptors, siRNA delivery, Trastuzumab",
author = "Hitesh Kulhari and Jangid, {Ashok K.} and Adams, {David J.}",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media, LLC, part of Springer Nature 2019.",
year = "2019",
doi = "10.1007/978-1-4939-9220-1_14",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "195--201",
booktitle = "Methods in Molecular Biology",
}