Multi-ink pattern generation by dip-pen nanolithography®

Jae Won Jang, Alexander Smetana, Paul Stiles

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Multiplexed patterns of hydrogels and phospholipids with fluorescent dyes are accomplished by dip-pen nanolithography® (DPN®). For example, four different dye-labeled hydrogel dot arrays are DPN® patterned within 50x50 μm2 area, and two different dye-doped phospholipids dots and letters with less than 1 μm line-width are also DPN® patterned. We demonstrate that multiink patterns with precise alignment are able to be printed by DPN® within a micron-scale. Moreover, this multi-ink DPN® patterning methodology can be extended to delicate bio-materials printing in a subcellular scale with accurate positioning control.

Original languageEnglish
Pages (from-to)24-29
Number of pages6
JournalScanning
Volume32
Issue number1
DOIs
StatePublished - Jan 2010

Keywords

  • Dip pen nanolithography
  • Multiplexing
  • Nanolithography platform (NLP)
  • Phospholipids
  • Poly(ethylene glycol)

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