TY - JOUR
T1 - Multifunctional nanoparticles
T2 - Recent progress in cancer therapeutics
AU - Seeta Rama Raju, G.
AU - Benton, Leah
AU - Pavitra, E.
AU - Yu, Jae Su
N1 - Publisher Copyright:
© 2015 Royal Society of Chemistry.
PY - 2015/7/21
Y1 - 2015/7/21
N2 - Although much progress has been made in treating cancers, cancer death rates in and around the United States are still high. Current treatments are either ineffective against some cancers or detrimental to patients, which decreases their quality of life. The use of nanotechnology in cancer therapy can potentially increase patient survival, reduce side effects, and reduce mortality rates because nanoparticles (NPs) have the potential to target only tumors and bypass healthy cells. NPs possess many features, including size, shape, charge, and composition, which allow them to carry chemotherapeutics to cancer cells. NPs can also be used in radiotherapy as radiosensitizers and in imaging as contrast agents. Many studies have performed in vitro and/or in vivo experiments on these particles in human and animal cell lines. This review discusses recent studies on different NPs and their potential use in cancer therapy.
AB - Although much progress has been made in treating cancers, cancer death rates in and around the United States are still high. Current treatments are either ineffective against some cancers or detrimental to patients, which decreases their quality of life. The use of nanotechnology in cancer therapy can potentially increase patient survival, reduce side effects, and reduce mortality rates because nanoparticles (NPs) have the potential to target only tumors and bypass healthy cells. NPs possess many features, including size, shape, charge, and composition, which allow them to carry chemotherapeutics to cancer cells. NPs can also be used in radiotherapy as radiosensitizers and in imaging as contrast agents. Many studies have performed in vitro and/or in vivo experiments on these particles in human and animal cell lines. This review discusses recent studies on different NPs and their potential use in cancer therapy.
UR - http://www.scopus.com/inward/record.url?scp=84939197382&partnerID=8YFLogxK
U2 - 10.1039/c5cc04643b
DO - 10.1039/c5cc04643b
M3 - Article
C2 - 26234539
AN - SCOPUS:84939197382
SN - 1359-7345
VL - 51
SP - 13248
EP - 13259
JO - Chemical Communications
JF - Chemical Communications
IS - 68
ER -