Multifunctional nanoparticles: Recent progress in cancer therapeutics

G. Seeta Rama Raju, Leah Benton, E. Pavitra, Jae Su Yu

Research output: Contribution to journalArticlepeer-review

133 Scopus citations

Abstract

Although much progress has been made in treating cancers, cancer death rates in and around the United States are still high. Current treatments are either ineffective against some cancers or detrimental to patients, which decreases their quality of life. The use of nanotechnology in cancer therapy can potentially increase patient survival, reduce side effects, and reduce mortality rates because nanoparticles (NPs) have the potential to target only tumors and bypass healthy cells. NPs possess many features, including size, shape, charge, and composition, which allow them to carry chemotherapeutics to cancer cells. NPs can also be used in radiotherapy as radiosensitizers and in imaging as contrast agents. Many studies have performed in vitro and/or in vivo experiments on these particles in human and animal cell lines. This review discusses recent studies on different NPs and their potential use in cancer therapy.

Original languageEnglish
Pages (from-to)13248-13259
Number of pages12
JournalChemical Communications
Volume51
Issue number68
DOIs
StatePublished - 21 Jul 2015

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